MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 562833 | Name: NIT

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NIT is an inhibitor of HIV-1 protease (HIV-1p).

Chemical Structure

NIT
CAS#299922-10-4

Theoretical Analysis

MedKoo Cat#: 562833

Name: NIT

CAS#: 299922-10-4

Chemical Formula: C15H7N3O4S2

Exact Mass: 356.9878

Molecular Weight: 357.35

Elemental Analysis: C, 50.42; H, 1.97; N, 11.76; O, 17.91; S, 17.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
NIT;
IUPAC/Chemical Name
4-Nitro-2-(2-thioxo-2,3-dihydro-benzothiazol-6-yl)-isoindole-1,3-dione
InChi Key
XZCFYWWZCCVGFB-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H7N3O4S2/c19-13-8-2-1-3-10(18(21)22)12(8)14(20)17(13)7-4-5-9-11(6-7)24-15(23)16-9/h1-6H,(H,16,23)
SMILES Code
O=C1N(C2=CC=C3NC(SC3=C2)=S)C(C4=C1C=CC=C4[N+]([O-])=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 357.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Siddiqui N, Asawa S, Birru B, Baadhe R, Rao S. PCL-Based Composite Scaffold Matrices for Tissue Engineering Applications. Mol Biotechnol. 2018 May 14. doi: 10.1007/s12033-018-0084-5. [Epub ahead of print] Review. PubMed PMID: 29761314. 2: Diwan B, Parkhey P, Gupta P. From agro-industrial wastes to single cell oils: a step towards prospective biorefinery. Folia Microbiol (Praha). 2018 Apr 23. doi: 10.1007/s12223-018-0602-7. [Epub ahead of print] Review. PubMed PMID: 29687420. 3: Yang L, Wen KS, Ruan X, Zhao YX, Wei F, Wang Q. Response of Plant Secondary Metabolites to Environmental Factors. Molecules. 2018 Mar 27;23(4). pii: E762. doi: 10.3390/molecules23040762. Review. PubMed PMID: 29584636. 4: Mohan A. Syngnathia-Congenital Maxillomandibular fusion: Case Report and Literature Review. J Oral Maxillofac Surg. 2018 May;76(5):1096.e1-1096.e6. doi: 10.1016/j.joms.2018.01.017. Epub 2018 Feb 2. Review. PubMed PMID: 29447830. 5: Berg RC, Winsvold A, Kornør H, Øverland S, Smedslund G, Hammerstrøm KT, Storetvedt K, Johnsen J, Hansen H, Tømmervik K. Effects of Opioid Agonist Treatment for Pregnant Opioid Dependent Women [Internet]. Oslo, Norway: Knowledge Centre for the Health Services at The Norwegian Institute of Public Health (NIPH); 2008 Nov. Available from http://www.ncbi.nlm.nih.gov/books/NBK464917/ PubMed PMID: 29320133. 6: Kaur Manjal S, Kaur R, Bhatia R, Kumar K, Singh V, Shankar R, Kaur R, Rawal RK. Synthetic and medicinal perspective of thiazolidinones: A review. Bioorg Chem. 2017 Dec;75:406-423. doi: 10.1016/j.bioorg.2017.10.014. Epub 2017 Oct 23. Review. PubMed PMID: 29102723. 7: Vimal A, Kumar A. Biotechnological production and practical application of L-asparaginase enzyme. Biotechnol Genet Eng Rev. 2017 Apr;33(1):40-61. doi: 10.1080/02648725.2017.1357294. Epub 2017 Aug 2. Review. PubMed PMID: 28766374. 8: Ebinger SM, Hardt J, Warschkow R, Schmied BM, Herold A, Post S, Marti L. Operative and medical treatment of chronic anal fissures-a review and network meta-analysis of randomized controlled trials. J Gastroenterol. 2017 Jun;52(6):663-676. doi: 10.1007/s00535-017-1335-0. Epub 2017 Apr 10. Review. PubMed PMID: 28396998. 9: Dheer D, Singh V, Shankar R. Medicinal attributes of 1,2,3-triazoles: Current developments. Bioorg Chem. 2017 Apr;71:30-54. doi: 10.1016/j.bioorg.2017.01.010. Epub 2017 Jan 18. Review. PubMed PMID: 28126288. 10: Zhang S, Wang Z. Effect of recombinant human brain natriuretic peptide (rhBNP) versus nitroglycerin in patients with heart failure: A systematic review and meta-analysis. Medicine (Baltimore). 2016 Nov;95(44):e4757. Review. PubMed PMID: 27858837; PubMed Central PMCID: PMC5591085. 11: Patel AK, Suri HS, Singh J, Kumar D, Shafique S, Nicolaides A, Jain SK, Saba L, Gupta A, Laird JR, Giannopoulos A, Suri JS. A Review on Atherosclerotic Biology, Wall Stiffness, Physics of Elasticity, and Its Ultrasound-Based Measurement. Curr Atheroscler Rep. 2016 Dec;18(12):83. Review. PubMed PMID: 27830569. 12: Londhe ND, Suri JS. Superharmonic Imaging for Medical Ultrasound: a Review. J Med Syst. 2016 Dec;40(12):279. Epub 2016 Oct 27. Review. PubMed PMID: 27787782. 13: Kumar A, Nayak BP, Kumar A. Obesity: single house for many evils. Minerva Endocrinol. 2016 Dec;41(4):499-508. Review. PubMed PMID: 27600644. 14: Koch E, Clark JM, Cohen B, Meinking TL, Ryan WG, Stevenson A, Yetman R, Yoon KS. Management of Head Louse Infestations in the United States-A Literature Review. Pediatr Dermatol. 2016 Sep;33(5):466-72. doi: 10.1111/pde.12982. Review. PubMed PMID: 27595869. 15: Amanzio M, Palermo S, Skyt I, Vase L. Lessons Learned From Nocebo Effects in Clinical Trials for Pain Conditions and Neurodegenerative Disorders. J Clin Psychopharmacol. 2016 Oct;36(5):475-82. doi: 10.1097/JCP.0000000000000556. Review. PubMed PMID: 27580494. 16: Panigrahy SK, Bhatt R, Kumar A. Reactive oxygen species: sources, consequences and targeted therapy in type 2 diabetes. J Drug Target. 2017 Feb;25(2):93-101. doi: 10.1080/1061186X.2016.1207650. Epub 2016 Jul 19. Review. PubMed PMID: 27356044. 17: Pia L, Garbarini F, Fossataro C, Burin D, Berti A. Sensing the body, representing the body: Evidence from a neurologically based delusion of body ownership. Cogn Neuropsychol. 2016 Feb-Mar;33(1-2):112-9. doi: 10.1080/02643294.2016.1185404. Epub 2016 Jun 17. Review. PubMed PMID: 27314302. 18: Mehrotra P. Biosensors and their applications - A review. J Oral Biol Craniofac Res. 2016 May-Aug;6(2):153-9. doi: 10.1016/j.jobcr.2015.12.002. Epub 2016 Jan 6. Review. PubMed PMID: 27195214; PubMed Central PMCID: PMC4862100. 19: Iannaccone M, D'Ascenzo F, Templin C, Omedè P, Montefusco A, Guagliumi G, Serruys PW, Di Mario C, Kochman J, Quadri G, Biondi-Zoccai G, Lüscher TF, Moretti C, D'amico M, Gaita F, Stone GW. Optical coherence tomography evaluation of intermediate-term healing of different stent types: systemic review and meta-analysis. Eur Heart J Cardiovasc Imaging. 2017 Feb;18(2):159-166. doi: 10.1093/ehjci/jew070. Epub 2016 Apr 20. Review. PubMed PMID: 27099274. 20: de Winter F, Kwok JC, Fawcett JW, Vo TT, Carulli D, Verhaagen J. The Chemorepulsive Protein Semaphorin 3A and Perineuronal Net-Mediated Plasticity. Neural Plast. 2016;2016:3679545. doi: 10.1155/2016/3679545. Epub 2016 Jan 14. Review. PubMed PMID: 27057361; PubMed Central PMCID: PMC4738953.

View History

Sorafenib free base

Sorafenib free base

New Featured