Synonym
Junceellin; (-)-Junceellin;
IUPAC/Chemical Name
(1R,3aR,4S,6S,7S,8R,8aR,9S,12aS,13S,13aR)-4-chloro-1,8a-dimethyl-5,12-dimethylene-2-oxotetradecahydro-5H-6,13a-epoxybenzo[4,5]cyclodeca[1,2-b]furan-7,8,9,13-tetrayl tetraacetate
InChi Key
PXWWTSQKNXBHTK-VQNAIMPISA-N
InChi Code
InChI=1S/C28H35ClO11/c1-11-9-10-18(35-14(4)30)27(8)19(11)23(37-16(6)32)28-13(3)26(34)39-24(28)20(29)12(2)21(40-28)22(36-15(5)31)25(27)38-17(7)33/h13,18-25H,1-2,9-10H2,3-8H3/t13-,18-,19+,20-,21-,22-,23-,24-,25-,27-,28+/m0/s1
SMILES Code
O=C1[C@H](C)[C@@]2([C@@H](OC(C)=O)[C@]3([H])[C@@]([C@@H](OC(C)=O)CCC3=C)(C)[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@](O2)([H])C([C@@H]4Cl)=C)[C@@]4([H])O1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
583.02
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Guo JZ, Liao XJ, Liu F, Xu SH. [Chemical constituents from Dichotella gemmacea]. Zhong Yao Cai. 2014 Feb;37(2):266-9. Chinese. PubMed PMID: 25095349.
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7: Garcia M, Rodriguez J, Jimenez C. Absolute structures of new briarane diterpenoids from junceella fragilis . J Nat Prod. 1999 Feb;62(2):257-60. PubMed PMID: 10075754.
8: Subrahmanyam C, Kulatheeswaran R, Ward RS. Briarane diterpenes from the Indian Ocean gorgonian Gorgonella umbraculum. J Nat Prod. 1998 Sep;61(9):1120-2. PubMed PMID: 9748378.
