Ornithine-methotrexate is a ornithine analog of methotrexate; inhibitors of dihydrofolate reductase. This decreases the tetrahydrofolate pool which then decreases synthesis of thymidyate and then inhibits DNA synthesis.
MedKoo Cat#: 591192
Name: Ornithine-methotrexate
CAS#: 80407-73-4
Chemical Formula: C20H25N9O3
Exact Mass: 439.2080
Molecular Weight: 439.48
Elemental Analysis: C, 54.66; H, 5.73; N, 28.68; O, 10.92
The following data is based on the product molecular weight 439.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
