MedKoo Cat#: 562827 | Name: DEHP
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

DEHP is an inducer of cell proliferation in lymphocytes.

Chemical Structure

DEHP
DEHP
CAS#117-81-7

Theoretical Analysis

MedKoo Cat#: 562827

Name: DEHP

CAS#: 117-81-7

Chemical Formula: C24H38O4

Exact Mass: 390.2770

Molecular Weight: 390.56

Elemental Analysis: C, 73.81; H, 9.81; O, 16.39

Price and Availability

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5g USD 250.00 2 Weeks
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Related CAS #
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Synonym
DEHP; Octyl phthalate; Fleximel; Etalon; Octoil
IUPAC/Chemical Name
bis(2-ethylhexyl) phthalate
InChi Key
BJQHLKABXJIVAM-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H38O4/c1-5-9-13-19(7-3)17-27-23(25)21-15-11-12-16-22(21)24(26)28-18-20(8-4)14-10-6-2/h11-12,15-16,19-20H,5-10,13-14,17-18H2,1-4H3
SMILES Code
O=C(OCC(CC)CCCC)C1=CC=CC=C1C(OCC(CC)CCCC)=O
Appearance
Liquid
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 390.56 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kashyap D, Agarwal T. Concentration and factors affecting the distribution of phthalates in the air and dust: A global scenario. Sci Total Environ. 2018 Apr 20;635:817-827. doi: 10.1016/j.scitotenv.2018.04.158. [Epub ahead of print] Review. PubMed PMID: 29710605. 2: Rowdhwal SSS, Chen J. Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview. Biomed Res Int. 2018 Feb 22;2018:1750368. doi: 10.1155/2018/1750368. eCollection 2018. Review. PubMed PMID: 29682520; PubMed Central PMCID: PMC5842715. 3: Lü H, Mo CH, Zhao HM, Xiang L, Katsoyiannis A, Li YW, Cai QY, Wong MH. Soil contamination and sources of phthalates and its health risk in China: A review. Environ Res. 2018 Jul;164:417-429. doi: 10.1016/j.envres.2018.03.013. Epub 2018 Mar 21. Review. PubMed PMID: 29573717. 4: Høyer BB, Lenters V, Giwercman A, Jönsson BAG, Toft G, Hougaard KS, Bonde JPE, Specht IO. Impact of Di-2-Ethylhexyl Phthalate Metabolites on Male Reproductive Function: a Systematic Review of Human Evidence. Curr Environ Health Rep. 2018 Mar;5(1):20-33. doi: 10.1007/s40572-018-0174-3. Review. PubMed PMID: 29468520. 5: Chou CK, Yang YT, Yang HC, Liang SS, Wang TN, Kuo PL, Wang HD, Tsai EM, Chiu CC. The Impact of Di(2-ethylhexyl)phthalate on Cancer Progression. Arch Immunol Ther Exp (Warsz). 2018 Jun;66(3):183-197. doi: 10.1007/s00005-017-0494-2. Epub 2017 Dec 5. Review. PubMed PMID: 29209738. 6: Tomita T. [Research on Insufficient Information for Pharmaceutical Products]. Yakugaku Zasshi. 2017;137(12):1497-1504. doi: 10.1248/yakushi.17-00164. Review. Japanese. PubMed PMID: 29199258. 7: Ginsberg GL, Belleggia G. Use of Monte Carlo analysis in a risk-based prioritization of toxic constituents in house dust. Environ Int. 2017 Dec;109:101-113. doi: 10.1016/j.envint.2017.06.009. Epub 2017 Sep 8. Review. PubMed PMID: 28890219. 8: Wassenaar PNH, Legler J. Systematic review and meta-analysis of early life exposure to di(2-ethylhexyl) phthalate and obesity related outcomes in rodents. Chemosphere. 2017 Dec;188:174-181. doi: 10.1016/j.chemosphere.2017.08.165. Epub 2017 Aug 31. Review. PubMed PMID: 28886551. 9: Li MC, Chen CH, Guo YL. Phthalate esters and childhood asthma: A systematic review and congener-specific meta-analysis. Environ Pollut. 2017 Oct;229:655-660. doi: 10.1016/j.envpol.2017.06.083. Epub 2017 Jul 7. Review. PubMed PMID: 28692937. 10: Li WC, Chow CF. Adverse child health impacts resulting from food adulterations in the Greater China Region. J Sci Food Agric. 2017 Sep;97(12):3897-3916. doi: 10.1002/jsfa.8405. Epub 2017 Jun 27. Review. PubMed PMID: 28466508. 11: Preciados M, Yoo C, Roy D. Estrogenic Endocrine Disrupting Chemicals Influencing NRF1 Regulated Gene Networks in the Development of Complex Human Brain Diseases. Int J Mol Sci. 2016 Dec 13;17(12). pii: E2086. Review. PubMed PMID: 27983596; PubMed Central PMCID: PMC5187886. 12: Giuseppe L, Lucia D, Marika M, Maria Grazia A, Silvia R, Eugenio P. Potential Health Hazards for Cumulative Exposures to Phthalates and Ionizing Radiation in High-Risk Pediatric Population. Mini Rev Med Chem. 2017;17(16):1502-1506. doi: 10.2174/1389557516666161031130200. Review. PubMed PMID: 27804887. 13: Zarean M, Keikha M, Poursafa P, Khalighinejad P, Amin M, Kelishadi R. A systematic review on the adverse health effects of di-2-ethylhexyl phthalate. Environ Sci Pollut Res Int. 2016 Dec;23(24):24642-24693. doi: 10.1007/s11356-016-7648-3. Epub 2016 Oct 6. Review. PubMed PMID: 27714658. 14: Zhang T, Shen W, De Felici M, Zhang XF. Di(2-ethylhexyl)phthalate: Adverse effects on folliculogenesis that cannot be neglected. Environ Mol Mutagen. 2016 Oct;57(8):579-588. doi: 10.1002/em.22037. Epub 2016 Aug 17. Review. PubMed PMID: 27530864. 15: Furihata C, Watanabe T, Suzuki T, Hamada S, Nakajima M. Collaborative studies in toxicogenomics in rodent liver in JEMS·MMS; a useful application of principal component analysis on toxicogenomics. Genes Environ. 2016 Aug 1;38:15. doi: 10.1186/s41021-016-0041-0. eCollection 2016. Review. PubMed PMID: 27482301; PubMed Central PMCID: PMC4968012. 16: Yaghjyan L, Ghita GL, Dumont-Driscoll M, Yost RA, Chang SH. Maternal exposure to di-2-ethylhexylphthalate and adverse delivery outcomes: A systematic review. Reprod Toxicol. 2016 Oct;65:76-86. doi: 10.1016/j.reprotox.2016.07.002. Epub 2016 Jul 10. Review. PubMed PMID: 27412369; PubMed Central PMCID: PMC5067201. 17: Ginsberg G, Ginsberg J, Foos B. Approaches to Children's Exposure Assessment: Case Study with Diethylhexylphthalate (DEHP). Int J Environ Res Public Health. 2016 Jul 1;13(7). pii: E670. doi: 10.3390/ijerph13070670. Review. PubMed PMID: 27376320; PubMed Central PMCID: PMC4962211. 18: Bowman JD, Choudhury M. Phthalates in neonatal health: friend or foe? J Dev Orig Health Dis. 2016 Dec;7(6):652-664. Epub 2016 Jul 4. Review. PubMed PMID: 27374623. 19: Martinez-Arguelles DB, Papadopoulos V. Prenatal phthalate exposure: epigenetic changes leading to lifelong impact on steroid formation. Andrology. 2016 Jul;4(4):573-84. doi: 10.1111/andr.12175. Epub 2016 Apr 4. Review. PubMed PMID: 27044004. 20: Wen Y, Liu SD, Lei X, Ling YS, Luo Y, Liu Q. Association of PAEs with Precocious Puberty in Children: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2015 Dec 1;12(12):15254-68. doi: 10.3390/ijerph121214974. Review. PubMed PMID: 26633449; PubMed Central PMCID: PMC4690910.