Synonym
Iopydone; Hytrast; Iopydonum; NSC 135284; NSC-135284; NSC135284;
IUPAC/Chemical Name
3,5-diiodopyridin-4(1H)-one
InChi Key
FRPFEVLOFNAKBS-UHFFFAOYSA-N
InChi Code
InChI=1S/C5H3I2NO/c6-3-1-8-2-4(7)5(3)9/h1-2H,(H,8,9)
SMILES Code
O=C1C(I)=CNC=C1I
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
346.89
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Bétrémieux P, Tréguier C, Pladys P, Bourdinière J, Leclech G, Lefrancois C. Tracheobronchography and balloon dilatation in acquired neonatal tracheal stenosis. Arch Dis Child Fetal Neonatal Ed. 1995 Jan;72(1):F3-7. PubMed PMID: 7743281; PubMed Central PMCID: PMC2528410.
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7: DE BRUIN CD. [COMPLICATIONS FOLLOWING BRONCHOGRAPHY WITH HYTRAST]. Ned Tijdschr Geneeskd. 1965 Apr 17;109:758-60. Dutch. PubMed PMID: 14320734.
8: MISENER FJ, QUINLAN JJ, HILTZ JE. HYTRAST: A NEW CONTRAST MEDIUM FOR BRONCHOGRAPHY. Can Med Assoc J. 1965 Mar 20;92:607-10. PubMed PMID: 14264971; PubMed Central PMCID: PMC1928217.
9: GREENBERG SD, HALLMAN GL Jr, SPJUT HJ. PULMONARY TISSUE REACTION FOLLOWING HYTRAST BRONCHOGRAMS. Ann Otol Rhinol Laryngol. 1964 Dec;73:1095-107. PubMed PMID: 14239528.
10: LIGHT JP, OSTER WF. STUDY OF THE CLINICAL AND PATHOLOGIC REACTION TO THE BRONCHOGRAPHIC AGENT HYTRAST. Am J Roentgenol Radium Ther Nucl Med. 1964 Sep;92:615-22. PubMed PMID: 14217082.
11: LANG EK. A COMPARATIVE STUDY OF FEBRILE REACTIONS TO HYTRAST, AQUEOUS DIONOSIL, AND OILY DIONOSIL IN BRONCHOGRAPHY. Radiology. 1964 Sep;83:455-9. PubMed PMID: 14206632.
12: OKADA H, MATSUMURA K. [BRONCHOGRAPHY WITH A NEW SUSPENSION CONTRAST MEDIA (HYTRAST)]. Rinsho Hoshasen. 1964 Jun;9:451-5. Japanese. PubMed PMID: 14182156.
13: GREENBERG SD, HALLMAN GL Jr, SPJUT HJ. PULMONARY TISSUE REACTION FOLLOWING HYTRAST BRONCHOGRAMS. Trans Annu Meet Am Bronchoesophagol Assoc. 1964;44:106-19. PubMed PMID: 14270817.
14: LEROUX BT, DUNCAN JG. BRONCHOGRAPHY WITH HYTRAST. Thorax. 1964 Jan;19:37-43. PubMed PMID: 14105882; PubMed Central PMCID: PMC1018797.
15: LAMY P, SENOT R, ANTHOINE D, JACQUIN B, RFBEIX G, BERTHEAU JM. [VALUE OF A NEW CONTRAST MEDIUM IN BRONCHOLOGY, AG 41-123 (HYTRAST)]. Ann Med Nancy. 1963 Nov;2:1523-31. French. PubMed PMID: 14111516.
16: WEBB WR, FITTS CT. EVALUATION OF HYTRAST AS A BRONCHOGRAPHIC MEDIUM. Am Surg. 1963 Jul;29:491-5. PubMed PMID: 14046051.
17: RAYL DF, SPJUT HJ. Bronchographic crystalline-inclusion pneumonia due to Hytrast. Radiology. 1963 Apr;80:588-604. PubMed PMID: 13973325.