MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 596276 | Name: Bitoscanate
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bitoscanate is an Anthelmintic.

Chemical Structure

Bitoscanate
Bitoscanate
CAS#4044-65-9

Theoretical Analysis

MedKoo Cat#: 596276

Name: Bitoscanate

CAS#: 4044-65-9

Chemical Formula: C8H4N2S2

Exact Mass: 191.9816

Molecular Weight: 192.25

Elemental Analysis: C, 49.98; H, 2.10; N, 14.57; S, 33.35

Price and Availability

Size Price Availability Quantity
1g USD 285.00 2 Weeks
5g USD 550.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Bitoscanate; Bitoscanatum; Phenylene thiocyanate; p-Phenylene diisothiocyanate; Benzene 1,4-Diisothiocyanate
IUPAC/Chemical Name
1,4-diisothiocyanatobenzene
InChi Key
OMWQUXGVXQELIX-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H4N2S2/c11-5-9-7-1-2-8(4-3-7)10-6-12/h1-4H
SMILES Code
S=C=NC1=CC=C(N=C=S)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 192.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lainakis NG, Papalois A, Agrogiannis G, Antonopoulos CN, Michail P, Bastounis E, Patsouris E, Felekouras E. Development of an animal model of fibrous cholangitis in pigs. J Invest Surg. 2014 Apr;27(2):95-101. doi: 10.3109/08941939.2013.839010. Epub 2014 Jan 10. PubMed PMID: 24410545. 2: Elshafey R, Tlili C, Abulrob A, Tavares AC, Zourob M. Label-free impedimetric immunosensor for ultrasensitive detection of cancer marker Murine double minute 2 in brain tissue. Biosens Bioelectron. 2013 Jan 15;39(1):220-5. doi: 10.1016/j.bios.2012.07.049. Epub 2012 Aug 3. PubMed PMID: 22898660. 3: Baccaro A, Steck AL, Marx A. Barcoded nucleotides. Angew Chem Int Ed Engl. 2012 Jan 2;51(1):254-7. doi: 10.1002/anie.201105717. Epub 2011 Nov 14. PubMed PMID: 22083884. 4: Sheng H, Ye BC. Different strategies of covalent attachment of oligonucleotide probe onto glass beads and the hybridization properties. Appl Biochem Biotechnol. 2009 Jan;152(1):54-65. doi: 10.1007/s12010-008-8245-9. Epub 2008 May 20. PubMed PMID: 18491234. 5: Bowen JM, Vitayavirasak B. Contractile activity and motility responses of the dog heartworm Dirofilaria immitis to classical anthelmintics and other compounds. Vet Parasitol. 2005 Nov 25;134(1-2):183-8. Epub 2005 Aug 1. PubMed PMID: 16076531. 6: Sugie S, Vinh PQ, Rahman KM, Ushida J, Kohno H, Suzuki R, Hara A, Quang le B, Tanaka T, Mori H. Suppressive effect of 1,4-phenylene diisothiocyanate on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice. Int J Cancer. 2005 Nov 20;117(4):524-30. Erratum in: Int J Cancer. 2005 Dec 20;117(6):1065. PubMed PMID: 15929075. 7: Benters R, Niemeyer CM, Wöhrle D. Dendrimer-activated solid supports for nucleic acid and protein microarrays. Chembiochem. 2001 Sep 3;2(9):686-94. PubMed PMID: 11828505. 8: Walsh MK, Wang X, Weimer BC. Optimizing the immobilization of single-stranded DNA onto glass beads. J Biochem Biophys Methods. 2001 Feb 26;47(3):221-31. PubMed PMID: 11245893. 9: Liang SP, Lee TT, Laursen RA. Single-step electroelution of proteins from SDS-polyacrylamide gels and immobilization on diisothiocyanate-glass beads in prepacked capillary columns for solid-phase microsequencing. Anal Biochem. 1991 Aug 15;197(1):163-7. PubMed PMID: 1952060. 10: Pappin DJ, Coull JM, Köster H. Solid-phase sequence analysis of proteins electroblotted or spotted onto polyvinylidene difluoride membranes. Anal Biochem. 1990 May 15;187(1):10-9. PubMed PMID: 2372105. 11: Periyasamy SM, Huang WH, Askari A. Subunit associations of (Na+ + K+)-dependent adenosine triphosphatase. Chemical cross-linking studies. J Biol Chem. 1983 Aug 25;258(16):9878-85. PubMed PMID: 6309787. 12: Ogawa T, Suruga K, Kojima Y, Kitahara T, Kuwabara N. Experimental study of the pathogenesis of infantile obstructive cholangiopathy and its clinical evaluation. J Pediatr Surg. 1983 Apr;18(2):131-5. PubMed PMID: 6854489. 13: Ogawa T, Suruga K, Kuwabara N. Experimental model of infantile obstructive cholangiopathy using 1,4-phenylenediisothiocyanate. Jpn J Surg. 1981;11(5):372-6. PubMed PMID: 7198165. 14: Werner GT. [Worm-diseases]. Fortschr Med. 1976 Jul 15;94(20-21):1165-71. German. PubMed PMID: 955553. 15: Samuel MR. Clinical experience with bitoscanate. Prog Drug Res. 1975;19:96-107. Review. PubMed PMID: 769080. 16: Patricia AH, Rao UP, Subramaniam R, Madanagopalan N. Experience with bitoscanate in adults. Prog Drug Res. 1975;19:90-5. PubMed PMID: 769079. 17: Mutalik GS, Gulati RB. Comparative study of bitoscanate, bephenium hydroxynaphthoate and tetrachlorethylene in hookworm disease. Prog Drug Res. 1975;19:86-9. PubMed PMID: 769078. 18: Mutalik GS, Gulati RB, Iqbal AK. A field trial with bitoscanate in India. Prog Drug Res. 1975;19:81-5. PubMed PMID: 769077. 19: Johnson S. A comparative study of bitoscanate, bephenium hydroxynaphthoate and tetrachlorethylene in hookworm infection. Prog Drug Res. 1975;19:70-4. PubMed PMID: 769076. 20: Harinasuta T, Bunnag D. Clinical field trial of bitoscanate in Necator americanus infection, South Thailand. Prog Drug Res. 1975;19:64-9. PubMed PMID: 769075.