MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 596259 | Name: Iodoantipyrine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Iodoantipyrine is a bioactive chemical.

Chemical Structure

Iodoantipyrine
Iodoantipyrine
CAS#129-81-7

Theoretical Analysis

MedKoo Cat#: 596259

Name: Iodoantipyrine

CAS#: 129-81-7

Chemical Formula: C11H11IN2O

Exact Mass: 313.9916

Molecular Weight: 314.12

Elemental Analysis: C, 42.06; H, 3.53; I, 40.40; N, 8.92; O, 5.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Iodoantipyrine; Arthripur; Iodophenazone; Jodantipyrine; EINECS 204-966-6;
IUPAC/Chemical Name
4-iodo-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one
InChi Key
ZZOBLCHCPLOXCE-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H11IN2O/c1-8-10(12)11(15)14(13(8)2)9-6-4-3-5-7-9/h3-7H,1-2H3
SMILES Code
O=C1N(C2=CC=CC=C2)N(C)C(C)=C1I
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 314.12 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Weiss HR, Chi OZ, Kiss GK, Liu X, Damito S, Jacinto E. Akt activation improves microregional oxygen supply/consumption balance after cerebral ischemia-reperfusion. Brain Res. 2018 Mar 15;1683:48-54. doi: 10.1016/j.brainres.2018.01.019. Epub 2018 Jan 31. PubMed PMID: 29371097. 2: Guo Y, Wang Z, Prathap S, Holschneider DP. Recruitment of prefrontal-striatal circuit in response to skilled motor challenge. Neuroreport. 2017 Dec 13;28(18):1187-1194. doi: 10.1097/WNR.0000000000000881. PubMed PMID: 28901999; PubMed Central PMCID: PMC5685897. 3: Wang Z, Chang HH, Gao Y, Zhang R, Guo Y, Holschneider DP, Rodriguez LV. Effects of water avoidance stress on peripheral and central responses during bladder filling in the rat: A multidisciplinary approach to the study of urologic chronic pelvic pain syndrome (MAPP) research network study. PLoS One. 2017 Sep 8;12(9):e0182976. doi: 10.1371/journal.pone.0182976. eCollection 2017. PubMed PMID: 28886046; PubMed Central PMCID: PMC5590813. 4: Bimpisidis Z, Öberg CM, Maslava N, Cenci MA, Lundblad C. Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l-DOPA in a rat model of Parkinson's disease. Exp Neurol. 2017 Jun;292:113-124. doi: 10.1016/j.expneurol.2017.03.006. Epub 2017 Mar 8. PubMed PMID: 28284817. 5: Wadsworth BJ, Pan J, Dude I, Colpo N, Bosiljcic M, Lin KS, Benard F, Bennewith KL. 2-(18)F-Fluoroethanol Is a PET Reporter of Solid Tumor Perfusion. J Nucl Med. 2017 May;58(5):815-820. doi: 10.2967/jnumed.116.183624. Epub 2017 Jan 26. PubMed PMID: 28126891. 6: Huang AC, Lu HC, Shyu BC. Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain. J Vis Exp. 2016 Jul 18;(113). doi: 10.3791/53947. PubMed PMID: 27500516. 7: Wang Z, Stefanko DP, Guo Y, Toy WA, Petzinger GM, Jakowec MW, Holschneider DP. Evidence of functional brain reorganization on the basis of blood flow changes in the CAG140 knock-in mouse model of Huntington's disease. Neuroreport. 2016 Jun 15;27(9):632-9. doi: 10.1097/WNR.0000000000000587. PubMed PMID: 27082842. 8: Holschneider DP, Guo Y, Mayer EA, Wang Z. Early life stress elicits visceral hyperalgesia and functional reorganization of pain circuits in adult rats. Neurobiol Stress. 2016 Jun 1;3:8-22. PubMed PMID: 26751119; PubMed Central PMCID: PMC4700548. 9: Chi OZ, Barsoum S, Vega-Cotto NM, Jacinto E, Liu X, Mellender SJ, Weiss HR. Effects of rapamycin on cerebral oxygen supply and consumption during reperfusion after cerebral ischemia. Neuroscience. 2016 Mar 1;316:321-7. doi: 10.1016/j.neuroscience.2015.12.045. Epub 2015 Dec 29. PubMed PMID: 26742793; PubMed Central PMCID: PMC4881736. 10: Chi OZ, Wu CC, Liu X, Rah KH, Jacinto E, Weiss HR. Restoration of Normal Cerebral Oxygen Consumption with Rapamycin Treatment in a Rat Model of Autism-Tuberous Sclerosis. Neuromolecular Med. 2015 Sep;17(3):305-13. doi: 10.1007/s12017-015-8359-5. Epub 2015 Jun 6. PubMed PMID: 26048361; PubMed Central PMCID: PMC4888058. 11: Lu HC, Chang WJ, Kuan YH, Huang AC, Shyu BC. A [14C]iodoantipyrine study of inter-regional correlations of neural substrates following central post-stroke pain in rats. Mol Pain. 2015 Mar 8;11:9. doi: 10.1186/s12990-015-0006-5. PubMed PMID: 25889278; PubMed Central PMCID: PMC4358859. 12: Chi OZ, Barsoum S, Rah KH, Liu X, Weiss HR. Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia. J Stroke Cerebrovasc Dis. 2015 Jun;24(6):1196-203. doi: 10.1016/j.jstrokecerebrovasdis.2015.01.016. Epub 2015 Apr 11. PubMed PMID: 25869775. 13: Lu HC, Chang WJ, Kuan YH, Huang AC, Shyu BC. A [(14)C]iodoantipyrine study of inter-regional correlations of neural substrates following central post-stroke pain in rats. Mol Pain. 2015 Dec;11(1):6. doi: 10.1186/s12990-015-0006-5. Epub 2015 Mar 8. PubMed PMID: 25775963. 14: Wang Z, Guo Y, Myers KG, Heintz R, Holschneider DP. Recruitment of the prefrontal cortex and cerebellum in Parkinsonian rats following skilled aerobic exercise. Neurobiol Dis. 2015 May;77:71-87. doi: 10.1016/j.nbd.2015.02.020. Epub 2015 Mar 3. PubMed PMID: 25747184; PubMed Central PMCID: PMC4402279. 15: Endepols H, Mertgens H, Backes H, Himmelreich U, Neumaier B, Graf R, Mies G. Longitudinal assessment of infarct progression, brain metabolism and behavior following anterior cerebral artery occlusion in rats. J Neurosci Methods. 2015 Sep 30;253:279-91. doi: 10.1016/j.jneumeth.2014.11.003. Epub 2014 Nov 11. PubMed PMID: 25445057. 16: Chi OZ, Grayson J, Barsoum S, Liu X, Dinani A, Weiss HR. Effects of dexmedetomidine on microregional O2 balance during reperfusion after focal cerebral ischemia. J Stroke Cerebrovasc Dis. 2015 Jan;24(1):163-70. doi: 10.1016/j.jstrokecerebrovasdis.2014.08.004. Epub 2014 Oct 5. PubMed PMID: 25294058. 17: Holschneider DP, Wang Z, Pang RD. Functional connectivity-based parcellation and connectome of cortical midline structures in the mouse: a perfusion autoradiography study. Front Neuroinform. 2014 Jun 11;8:61. doi: 10.3389/fninf.2014.00061. eCollection 2014. PubMed PMID: 24966831; PubMed Central PMCID: PMC4052632. 18: Liu F, McCullough LD. The middle cerebral artery occlusion model of transient focal cerebral ischemia. Methods Mol Biol. 2014;1135:81-93. doi: 10.1007/978-1-4939-0320-7_7. PubMed PMID: 24510856. 19: Wang Z, Myers KG, Guo Y, Ocampo MA, Pang RD, Jakowec MW, Holschneider DP. Functional reorganization of motor and limbic circuits after exercise training in a rat model of bilateral parkinsonism. PLoS One. 2013 Nov 21;8(11):e80058. doi: 10.1371/journal.pone.0080058. eCollection 2013. PubMed PMID: 24278239; PubMed Central PMCID: PMC3836982. 20: Weiss HR, Grayson J, Liu X, Barsoum S, Shah H, Chi OZ. Cerebral ischemia and reperfusion increases the heterogeneity of local oxygen supply/consumption balance. Stroke. 2013 Sep;44(9):2553-8. doi: 10.1161/STROKEAHA.113.001172. Epub 2013 Jul 9. PubMed PMID: 23839504.

View History

AT 61

AT 61