Synonym
WST-1; WST 1; WST1;
IUPAC/Chemical Name
Sodium 4-[2-(4-iodophenyl)-3-(4-nitrophenyl)tetrazol-2-ium-5-yl]benzene-1,3-disulfonate
InChi Key
JUJBNYBVVQSIOU-UHFFFAOYSA-M
InChi Code
InChI=1S/C19H12IN5O8S2.Na/c20-12-1-3-13(4-2-12)23-21-19(22-24(23)14-5-7-15(8-6-14)25(26)27)17-10-9-16(34(28,29)30)11-18(17)35(31,32)33;/h1-11H,(H-,28,29,30,31,32,33);/q;+1/p-1
SMILES Code
O=S(C1=CC=C(C2=NN(C3=CC=C([N+]([O-])=O)C=C3)[N+](C4=CC=C(I)C=C4)=N2)C(S(=O)([O-])=O)=C1)([O-])=O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
|
Solvent |
mg/mL |
mM |
| Solubility |
| DMSO |
10.0 |
0.00 |
| Water |
0.0 |
0.00 |
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.
Preparing Stock Solutions
The following data is based on the
product
molecular weight
651.33
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Bahadar H, Maqbool F, Niaz K, Abdollahi M. Toxicity of Nanoparticles and an Overview of Current Experimental Models. Iran Biomed J. 2016;20(1):1-11. Epub 2015 Aug 19. Review. PubMed PMID: 26286636; PubMed Central PMCID: PMC4689276.
2: Błaszczak-Świątkiewicz K, Mikiciuk-Olasik E. Some characteristics of activity of potential chemotherapeutics--benzimidazole derivatives. Adv Med Sci. 2015 Mar;60(1):125-32. doi: 10.1016/j.advms.2015.01.004. Epub 2015 Jan 21. Review. PubMed PMID: 25725479.
3: Tournebize J, Sapin-Minet A, Bartosz G, Leroy P, Boudier A. Pitfalls of assays devoted to evaluation of oxidative stress induced by inorganic nanoparticles. Talanta. 2013 Nov 15;116:753-63. doi: 10.1016/j.talanta.2013.07.077. Epub 2013 Aug 7. Review. PubMed PMID: 24148470.
4: Winkler C, Schäfer L, Felthaus O, Allerdings J, Hahnel S, Behr M, Bürgers R. The bacterial adhesion on and the cytotoxicity of various dental cements used for implant-supported fixed restorations. Acta Odontol Scand. 2014 May;72(4):241-50. doi: 10.3109/00016357.2013.828320. Epub 2013 Sep 30. Review. PubMed PMID: 24074394.
5: Berridge MV, Herst PM, Tan AS. Tetrazolium dyes as tools in cell biology: new insights into their cellular reduction. Biotechnol Annu Rev. 2005;11:127-52. Review. PubMed PMID: 16216776.
6: Scarlett DJ, Herst P, Tan A, Prata C, Berridge M. Mitochondrial gene-knockout (rho0) cells: a versatile model for exploring the secrets of trans-plasma membrane electron transport. Biofactors. 2004;20(4):199-206. Review. PubMed PMID: 15706057.
7: Glasow A, Bornstein SR. Leptin and the adrenal gland. Eur J Clin Invest. 2000 Dec;30 Suppl 3:39-45. Review. Erratum in: Eur J Clin Invest 2001 Jun;31(6):554. PubMed PMID: 11281366.
8: Berridge MV, Tan AS. High-capacity redox control at the plasma membrane of mammalian cells: trans-membrane, cell surface, and serum NADH-oxidases. Antioxid Redox Signal. 2000 Summer;2(2):231-42. Review. PubMed PMID: 11229528.
