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MedKoo Cat#: 596173 | Name: Jatropholone A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Jatropholone A is a diterpene derivative of jarophone.

Chemical Structure

Jatropholone A
Jatropholone A
CAS#71424-66-3

Theoretical Analysis

MedKoo Cat#: 596173

Name: Jatropholone A

CAS#: 71424-66-3

Chemical Formula: C20H24O2

Exact Mass: 296.1776

Molecular Weight: 296.41

Elemental Analysis: C, 81.04; H, 8.16; O, 10.80

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Jatropholone A; CCRIS 1441; CCRIS-1441; CCRIS1441;
IUPAC/Chemical Name
(5S,9aS)-3-hydroxy-1,1,2,5-tetramethyl-7-methylene-1,4,5,6a,7,8,9,9a-octahydro-6H-cyclopropa[3,4]cyclohepta[1,2-e]inden-6-one
InChi Key
OMPZQJSZAWAPFB-POKWKQQTSA-N
InChi Code
InChI=1S/C20H24O2/c1-9-8-13-12(15-10(2)16(15)18(9)21)6-7-14-17(13)19(22)11(3)20(14,4)5/h9,14,16,22H,2,6-8H2,1,3-5H3/t9-,14+,16?/m0/s1
SMILES Code
O=C([C@@H](C)C1)C2C(C2=C)=C3C1=C4C(O)=C(C)C(C)(C)[C@]4([H])CC3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 296.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Theoduloz C, Rodríguez JA, Pertino M, Schmeda-Hirschmann G. Antiproliferative activity of the diterpenes jatrophone and jatropholone and their derivatives. Planta Med. 2009 Nov;75(14):1520-2. doi: 10.1055/s-0029-1185834. Epub 2009 Jun 26. PubMed PMID: 19562659. 2: Pertino M, Schmeda-Hirschmann G, Rodríguez JA, Theoduloz C. Gastroprotective effect and cytotoxicity of semisynthetic jatropholone derivatives. Planta Med. 2007 Aug;73(10):1095-100. Epub 2007 Aug 9. PubMed PMID: 17691058. 3: Pertino M, Schmeda-Hirschmann G, Rodríguez JA, Theoduloz C. Gastroprotective effect and cytotoxicity of terpenes from the Paraguayan crude drug "yagua rova" (Jatropha isabelli). J Ethnopharmacol. 2007 May 22;111(3):553-9. Epub 2007 Jan 7. PubMed PMID: 17276635.

View History

JC-171

JC-171