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MedKoo Cat#: 591141 | Name: Methylrosanilinium chloride
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Methylrosanilinium chloride is a dye that is a mixture of violet rosanilinis with antibacterial, antifungal, and anthelmintic properties.

Chemical Structure

Methylrosanilinium chloride
Methylrosanilinium chloride
CAS#548-62-9

Theoretical Analysis

MedKoo Cat#: 591141

Name: Methylrosanilinium chloride

CAS#: 548-62-9

Chemical Formula: C25H30ClN3

Exact Mass: 407.2128

Molecular Weight: 407.99

Elemental Analysis: C, 73.60; H, 7.41; Cl, 8.69; N, 10.30

Price and Availability

Size Price Availability Quantity
25g USD 250.00 2 weeks
100g USD 550.00 2 weeks
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Related CAS #
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Synonym
Methylrosanilinium chloride; Crystal Violet; Basic Violet 3; Hexamethylpararosaniline Chloride; Gentian Violet
IUPAC/Chemical Name
(4-(4,4'-Bis(dimethylamino)benzhydrylidene)cyclohexa-2,5-dien-1-ylidene)dimethylammonium chloride
InChi Key
ZXJXZNDDNMQXFV-UHFFFAOYSA-M
InChi Code
InChI=1S/C25H30N3.ClH/c1-26(2)22-13-7-19(8-14-22)25(20-9-15-23(16-10-20)27(3)4)21-11-17-24(18-12-21)28(5)6;/h7-18H,1-6H3;1H/q+1;/p-1
SMILES Code
C/[N+](C)=C1C=C/C(C=C/1)=C(C2=CC=C(N(C)C)C=C2)\C3=CC=C(N(C)C)C=C3.[Cl-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Product Data
Instruction
View handling instruction
Biological target:
Crystal Violet (Gentian Violet) has antiviral effects against H1N1 and also has prominent bactericidal activities.
In vitro activity:
This study examined the antiviral activity of gentian violet (GV) and GV-dyed cloth against the influenza A (H1N1) virus. Time-kill studies were carried out, and the virus titer was determined based on the 50% tissue culture infective dose (TCID50). The minimum inhibitory concentrations (MICs) of GV against bacteria were also determined, and the killing activities of the GV-dyed cloth were judged from viable cell counts. GV immediately killed the influenza A virus and this was confirmed by electron microscopy. Reference: J Infect Chemother. 2006 Apr;12(2):73-9. https://pubmed.ncbi.nlm.nih.gov/16648946/
In vivo activity:
Crystal violet exhibited characteristics of an uncoupler of oxidative phosphorylation, i.e. it released respiratory control, hindered ATP synthesis, enhanced ATPase activity, and produced swelling of isolated rat liver mitochondria. Maximal stimulation of respiration, ATPase activity, and swelling was observed at a concentration of 40 microM. The inhibition of State 3 respiration by oligomycin was released by crystal violet. High concentrations of crystal violet inhibited mitochondrial respiration. Reference: J Biol Chem. 1988 Sep 5;263(25):12493-9. https://pubmed.ncbi.nlm.nih.gov/2970460/
Solvent mg/mL mM comments
Solubility
DMSO 91.0 223.05
Ethanol 8.0 19.61
Water 9.5 23.29
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 407.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
1. Nagayama A. Inactivation of influenza A virus by gentian violet (GV) and GV-dyed cotton cloth, and bactericidal activities of these agents. J Infect Chemother. 2006 Apr;12(2):73-9. doi: 10.1007/s10156-005-0426-7. PMID: 16648946; PMCID: PMC7087860. 2. Beveridge TJ, Schultze-Lam S. The response of selected members of the archaea to the gram stain. Microbiology (Reading). 1996 Oct;142 ( Pt 10):2887-95. doi: 10.1099/13500872-142-10-2887. PMID: 8885405. 3. Moreno SN, Gadelha FR, Docampo R. Crystal violet as an uncoupler of oxidative phosphorylation in rat liver mitochondria. J Biol Chem. 1988 Sep 5;263(25):12493-9. PMID: 2970460.
In vitro protocol:
1. Nagayama A. Inactivation of influenza A virus by gentian violet (GV) and GV-dyed cotton cloth, and bactericidal activities of these agents. J Infect Chemother. 2006 Apr;12(2):73-9. doi: 10.1007/s10156-005-0426-7. PMID: 16648946; PMCID: PMC7087860. 2. Beveridge TJ, Schultze-Lam S. The response of selected members of the archaea to the gram stain. Microbiology (Reading). 1996 Oct;142 ( Pt 10):2887-95. doi: 10.1099/13500872-142-10-2887. PMID: 8885405.
In vivo protocol:
1. Moreno SN, Gadelha FR, Docampo R. Crystal violet as an uncoupler of oxidative phosphorylation in rat liver mitochondria. J Biol Chem. 1988 Sep 5;263(25):12493-9. PMID: 2970460.