MedKoo Cat#: 591137 | Name: 3'-Adenylic acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

3'-Adenylic acid, also known as Adenosine 3′-monophosphate (3′-AMP), is a metabolite produced from hydrolysis of 2′,3′-cAMP by a family of metal-dependent phosphodiesterases. 3′-AMP inhibits proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors. 2′,3′-cAMP and 3′-AMP represent a new unexplored pathway for adenosine-based cell regulation.

Chemical Structure

3'-Adenylic acid
3'-Adenylic acid
CAS#84-21-9

Theoretical Analysis

MedKoo Cat#: 591137

Name: 3'-Adenylic acid

CAS#: 84-21-9

Chemical Formula: C10H14N5O7

Exact Mass: 347.0631

Molecular Weight: 347.22

Elemental Analysis: C, 34.59; H, 4.06; N, 20.17; O, 32.25; P, 8.92

Price and Availability

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100mg USD 450.00 Back order
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Related CAS #
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Synonym
3'-Adenylic acid; Adenosine 3′-monophosphate; 3'-AMP.
IUPAC/Chemical Name
Adenosine 3'-phosphate
InChi Key
LNQVTSROQXJCDD-KQYNXXCUSA-N
InChi Code
InChI=1S/C10H14N5O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-6(17)7(4(1-16)21-10)22-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
SMILES Code
OC[C@@H]1[C@@H](OP(O)(O)=O)[C@H]([C@H](N2C=NC3=C(N=CN=C32)N)O1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 347.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yanagawa H, Ogawa Y, Miyakawa A, Egami F. DNase A, a poly(dA) and poly(dT)-specific deoxyribonuclease from Achatina fulica. Purification and characterization. J Biochem. 1981 Nov;90(5):1463-78. PubMed PMID: 7338515. 2: Iizuka H, Adachi K, Halprin KM, Levine V. Adenosine and adenine nucleotides stimulation of skin (epidermal) adenylate cyclase. Biochim Biophys Acta. 1976 Oct 22;444(3):685-93. PubMed PMID: 186102.