Synonym
Barium lithol red; PR-258; 1883 red; Barium lithol; HSDB 5523; Red No. 207; Light Red RB; Pigment Red 49:1;
IUPAC/Chemical Name
1-Naphthalenesulfonic acid, 2-((2-hydroxy-1-naphthalenyl)azo)-, barium salt (2:1)
InChi Key
LFZDEAVRTJKYAF-JTVZJQPRSA-L
InChi Code
InChI=1S/2C20H14N2O4S.Ba/c2*23-18-12-10-13-5-1-3-7-15(13)19(18)22-21-17-11-9-14-6-2-4-8-16(14)20(17)27(24,25)26;/h2*1-12,23H,(H,24,25,26);/q;;+2/p-2/b2*22-21+;
SMILES Code
O=S(C1=C2C=CC=CC2=CC=C1/N=N/C3=C4C=CC=CC4=CC=C3O)([O-])=O.O=S(C5=C6C=CC=CC6=CC=C5/N=N/C7=C8C=CC=CC8=CC=C7O)([O-])=O.[Ba+2]
Purity
>70% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
892.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Kennedy AR, Stewart H, Eremin K, Stenger J. Lithol Red: a systematic structural study on salts of a sulfonated azo pigment. Chemistry. 2012 Mar 5;18(10):3064-9. doi: 10.1002/chem.201103027. Epub 2012 Feb 1. PubMed PMID: 22298463.
2: Inoue T, Kamikura M, Murakami N. [Dye standards of National Institute of Hygienic Sciences, "lithol rubine BCA standard", "lake red C standard" and "lake red CBA standard"]. Eisei Shikenjo Hokoku. 1968;86:136-9. Japanese. PubMed PMID: 5753657.
3: Chung KT, Fulk GE, Andrews AW. Mutagenicity testing of some commonly used dyes. Appl Environ Microbiol. 1981 Oct;42(4):641-8. PubMed PMID: 7039509; PubMed Central PMCID: PMC244076.
4: Kgzuka T, Tashiro M, Sano S, Fujimoto K, Nakamura Y, Hashimoto S, Nakaminami G. Pigmented contact dermatitis from azo dyes. I. Cross-sensitivity in humans. Contact Dermatitis. 1980 Aug;6(5):330-6. PubMed PMID: 7418389.
5: Chung KT. The significance of azo-reduction in the mutagenesis and carcinogenesis of azo dyes. Mutat Res. 1983 Apr;114(3):269-81. Review. PubMed PMID: 6339890.
6: Chung KT, Stevens SE Jr, Cerniglia CE. The reduction of azo dyes by the intestinal microflora. Crit Rev Microbiol. 1992;18(3):175-90. Review. PubMed PMID: 1554423.
7: Yang G, Lee HE, Lim KM, Choi YK, Kim KB, Lee BM, Lee JY. Potentiation of skin TSLP production by a cosmetic colorant leads to aggravation of dermatitis symptoms. Chem Biol Interact. 2018 Mar 25;284:41-47. doi: 10.1016/j.cbi.2018.02.020. Epub 2018 Feb 17. PubMed PMID: 29462589.
