MedKoo Cat#: 581238 | Name: Daigremontianin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Daigremontianin is a bufadienolide. Bufadienolides are steroids and cardiac glycoside aglycones (meaning that they bind with carbohydrates to form cardiac glycosides) that are similar to cardenolides, differing only in the structure of the C-17 substituent on the D ring. This chemical has been found to be toxic in experiments on mice, it is one of five bufadienolides that have been isolated from Kalanchoe daigremontiana.

Chemical Structure

Daigremontianin
Daigremontianin
CAS#98205-50-6

Theoretical Analysis

MedKoo Cat#: 581238

Name: Daigremontianin

CAS#: 98205-50-6

Chemical Formula: C26H30O9

Exact Mass: 486.1890

Molecular Weight: 486.52

Elemental Analysis: C, 64.19; H, 6.22; O, 29.60

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Daigremontianin;
IUPAC/Chemical Name
(2S,4S,6R,6aR,6bS,7S,8aR,9R,11aS,11bR,13aR)-7,11a-dihydroxy-2,8a-dimethyl-8-oxo-9-(2-oxo-2H-pyran-5-yl)dodecahydro-4H-2,6-epoxy-4,13a-methanocyclopenta[5,6]naphtho[2,1-d][1,3]dioxocine-6a(6bH)-carbaldehyde
InChi Key
PHOLEJIIASOWOL-NGDBJROISA-N
InChi Code
InChI=1S/C26H30O9/c1-22-15(13-3-4-18(28)32-11-13)6-8-26(22,31)16-5-7-24-10-14-9-17(34-23(2,33-14)35-24)25(24,12-27)19(16)20(29)21(22)30/h3-4,11-12,14-17,19-20,29,31H,5-10H2,1-2H3/t14-,15+,16+,17+,19+,20-,22-,23-,24+,25+,26-/m0/s1
SMILES Code
C1[C@H]2C[C@@]34[C@@]([C@@H]1O[C@@](O2)(C)O4)(C=O)[C@@H]1[C@@H](CC3)[C@]2(O)[C@](C)(C(=O)[C@H]1O)[C@@H](c1ccc(oc1)=O)CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 486.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wagner H, Fischer M, Lotter H. Isolation and structure determination of daigremontianin, a novel bufadienolide from Kalanchoe daigremontiana. Planta Med. 1985 Apr;(2):169-70. PubMed PMID: 3839925.