Adamantane diazirine | CAS# 41736-95-2

MedKoo Cat#: 591071 | Name: Adamantane diazirine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Adamantane diazirine is a biochemical.

Chemical Structure

Adamantane diazirine

CAS#41736-95-2

Theoretical Analysis

MedKoo Cat#: 591071

Name: Adamantane diazirine

CAS#: 41736-95-2

Chemical Formula: C10H14N2

Exact Mass: 162.1157

Molecular Weight: 162.24

Elemental Analysis: C, 74.03; H, 8.70; N, 17.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Adamantane diazirine

IUPAC/Chemical Name

Spiro(3H-diazirine-3,2'-tricyclo(3.3.1.1(3,7))decane)

InChi Key

PNVXTJMLAFYDOJ-UHFFFAOYSA-N

InChi Code

InChI=1S/C10H14N2/c1-6-2-8-4-7(1)5-9(3-6)10(8)11-12-10/h6-9H,1-5H2

SMILES Code

C(C12N=N1)(C3)CC4CC3CC2C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 162.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Miller JP, White RE. Photoaffinity labeling of cytochrome P450 2B4: capture of active site heme ligands by a photocarbene. Biochemistry. 1994 Jan 25;33(3):807-17. PubMed PMID: 8292609. 2: Krieg UC, Isaacs BS, Yemul SS, Esmon CT, Bayley H, Johnson AE. Interaction of blood coagulation factor Va with phospholipid vesicles examined by using lipophilic photoreagents. Biochemistry. 1987 Jan 13;26(1):103-9. PubMed PMID: 3828292. 3: Zhang YZ, Georgevich G, Capaldi RA. Topology of beef heart cytochrome c oxidase from studies on reconstituted membranes. Biochemistry. 1984 Nov 6;23(23):5616-21. PubMed PMID: 6095902. 4: Nicholas RA. Purification of the membrane-spanning tryptic peptides of the alpha polypeptide from sodium and potassium ion activated adenosinetriphosphatase labeled with 1-tritiospiro[adamantane-4,3'-diazirine]. Biochemistry. 1984 Feb 28;23(5):888-98. PubMed PMID: 6324857. 5: Middlemas DS, Raftery MA. Exposure of acetylcholine receptor to the lipid bilayer. Biochem Biophys Res Commun. 1983 Sep 30;115(3):1075-82. PubMed PMID: 6626218. 6: Farley RA. Identification of hydrophobic regions of the calcium-transport ATPase from sarcoplasmic reticulum after photochemical labeling with adamantane diazirine. Int J Biochem. 1983;15(12):1423-7. PubMed PMID: 6228448. 7: Bayley H, Knowles JR. Photogenerated reagents for membranes: selective labeling of intrinsic membrane proteins in the human erythrocyte membrane. Biochemistry. 1980 Aug 19;19(17):3883-92. PubMed PMID: 7407075. 8: Farley RA, Goldman DW, Bayley H. Identification of regions of the catalytic subunit of (Na-K)-ATPase embedded within the cell membrane. Photochemical labeling with [3H]adamantane diazirine. J Biol Chem. 1980 Feb 10;255(3):860-4. PubMed PMID: 6243299. 9: Bayley H, Knowles JR. Photogenerated, hydrophobic reagents for intrinsic membrane proteins. Ann N Y Acad Sci. 1980;346:45-58. PubMed PMID: 6930191. 10: Kaufman JF, Strominger JL. Both chains of HLA-DR bind to the membrane with a penultimate hydrophobic region and the heavy chain is phosphorylated at its hydrophilic carboxyl terminus. Proc Natl Acad Sci U S A. 1979 Dec;76(12):6304-8. PubMed PMID: 293722; PubMed Central PMCID: PMC411852.