MedKoo Cat#: 591057 | Name: AD-1491

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AD-1491 is a bioactive chemical.

Chemical Structure

AD-1491
CAS#76302-29-9

Theoretical Analysis

MedKoo Cat#: 591057

Name: AD-1491

CAS#: 76302-29-9

Chemical Formula: C14H14N2O2

Exact Mass: 242.1055

Molecular Weight: 242.28

Elemental Analysis: C, 69.41; H, 5.82; N, 11.56; O, 13.21

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
InChI=1S/C14H14N2O2/c1-10(14(17)18)11-5-7-12(8-6-11)16-13-4-2-3-9-15-13/h2-10H,1H3,(H,15,16)(H,17,18)
Synonym
AD-1491; AD1491; AD1491
IUPAC/Chemical Name
Hydratropic acid, p-(2-pyridinylamino)-
InChi Key
AHBKHOGVLKUYAT-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H14N2O2/c1-10(14(17)18)11-5-7-12(8-6-11)16-13-4-2-3-9-15-13/h2-10H,1H3,(H,15,16)(H,17,18)
SMILES Code
CC(C1=CC=C(NC2=NC=CC=C2)C=C1)C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 242.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Ambrosi M, Orsini A, Verrotti A, Striano P. Medical management for neurosurgical related seizures. Expert Opin Pharmacother. 2017 Oct;18(14):1491-1498. doi: 10.1080/14656566.2017.1373092. Epub 2017 Sep 1. Review. PubMed PMID: 28847180. 2: Wengert GJ, Baltzer PAT, Bickel H, Thurner P, Breitenseher J, Lazar M, Pones M, Peck-Radosavljevic M, Hucke F, Ba-Ssalamah A. Differentiation of Intrahepatic Cholangiocellular Carcinoma from Hepatocellular Carcinoma in the Cirrhotic Liver Using Contrast-enhanced MR Imaging. Acad Radiol. 2017 Dec;24(12):1491-1500. doi: 10.1016/j.acra.2017.06.005. Epub 2017 Jul 26. PubMed PMID: 28756085. 3: Gao C, Zhou Y, Jiang Z, Zhao Y, Zhang D, Cong X, Cao R, Li H, Tian W. Cytotoxic and chemosensitization effects of Scutellarin from traditional Chinese herb Scutellaria altissima L. in human prostate cancer cells. Oncol Rep. 2017 Sep;38(3):1491-1499. doi: 10.3892/or.2017.5850. Epub 2017 Jul 24. PubMed PMID: 28737827; PubMed Central PMCID: PMC5549025. 4: Chen T, Tanaka M, Wang Y, Sha S, Furuya K, Chen L, Sokabe M. Neurosteroid dehydroepiandrosterone enhances activity and trafficking of astrocytic GLT-1 via σ(1) receptor-mediated PKC activation in the hippocampal dentate gyrus of rats. Glia. 2017 Sep;65(9):1491-1503. doi: 10.1002/glia.23175. Epub 2017 Jun 5. PubMed PMID: 28581152. 5: Huang JJ, Chen B, Hu J, Yang WH. Limited sampling strategy for predicting busulfan exposure in hematopoietic stem cell transplantation recipients. Int J Clin Pharm. 2017 Aug;39(4):662-668. doi: 10.1007/s11096-017-0481-z. Epub 2017 May 29. PubMed PMID: 28555420. 6: Staikou C, Kalampokas T, Kalampokas E, Vassiloglou S, Paraskeva A. Epidural fentanyl does not affect cervical dilation and progress of first stage of vaginal delivery: a randomized, double-blind study. Curr Med Res Opin. 2017 Aug;33(8):1491-1496. doi: 10.1080/03007995.2017.1321536. Epub 2017 May 24. PubMed PMID: 28425307. 7: Mizrahy S, Hazan-Halevy I, Dammes N, Landesman-Milo D, Peer D. Current Progress in Non-viral RNAi-Based Delivery Strategies to Lymphocytes. Mol Ther. 2017 Jul 5;25(7):1491-1500. doi: 10.1016/j.ymthe.2017.03.001. Epub 2017 Apr 6. Review. PubMed PMID: 28392163; PubMed Central PMCID: PMC5498814. 8: Lamb T, de Haro L, Lonati D, Brvar M, Eddleston M. Antivenom for European Vipera species envenoming. Clin Toxicol (Phila). 2017 Jul;55(6):557-568. doi: 10.1080/15563650.2017.1300261. Epub 2017 Mar 28. Review. PubMed PMID: 28349771. 9: DePry JL, Mann M. Successful Treatment of Postoperative Pain After Mohs Micrographic Surgery With Onabotulinum Toxin A. Dermatol Surg. 2017 Dec;43(12):1491-1494. doi: 10.1097/DSS.0000000000001124. PubMed PMID: 28323649. 10: Yi L, Cheng D, Zhang K, Huo X, Mo Y, Shi H, Di H, Zou Y, Zhang H, Zhao J, Xu Y, Erle DJ, Zhen G. Intelectin contributes to allergen-induced IL-25, IL-33, and TSLP expression and type 2 response in asthma and atopic dermatitis. Mucosal Immunol. 2017 Nov;10(6):1491-1503. doi: 10.1038/mi.2017.10. Epub 2017 Feb 22. PubMed PMID: 28224996; PubMed Central PMCID: PMC5568519. 11: Rimessi A, Pavan C, Ioannidi E, Nigro F, Morganti C, Brugnoli A, Longo F, Gardin C, Ferroni L, Morari M, Vindigni V, Zavan B, Pinton P. Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain. Neuropsychopharmacology. 2017 Jun;42(7):1491-1501. doi: 10.1038/npp.2017.20. Epub 2017 Jan 27. PubMed PMID: 28128334; PubMed Central PMCID: PMC5436118. 12: McMichael CN, Matthews-Bird F, Farfan-Rios W, Feeley KJ. Ancient human disturbances may be skewing our understanding of Amazonian forests. Proc Natl Acad Sci U S A. 2017 Jan 17;114(3):522-527. doi: 10.1073/pnas.1614577114. Epub 2017 Jan 3. PubMed PMID: 28049821; PubMed Central PMCID: PMC5255623. 13: Dioguardi Burgio M, Ronot M, Bruno O, Francoz C, Paradis V, Castera L, Durand F, Soubrane O, Vilgrain V. Correlation of tumor response on computed tomography with pathological necrosis in hepatocellular carcinoma treated by chemoembolization before liver transplantation. Liver Transpl. 2016 Nov;22(11):1491-1500. doi: 10.1002/lt.24615. PubMed PMID: 27543821. 14: Garcia-Prats AJ, Schaaf HS, Hesseling AC. The safety and tolerability of the second-line injectable antituberculosis drugs in children. Expert Opin Drug Saf. 2016 Nov;15(11):1491-1500. Epub 2016 Aug 22. Review. PubMed PMID: 27548570. 15: Rosa GM, Bianco D, Valbusa A, Massobrio L, Chiarella F, Brunelli C. Pharmacokinetics and pharmacodynamics of ticagrelor in the treatment of cardiac ischemia. Expert Opin Drug Metab Toxicol. 2016 Dec;12(12):1491-1502. Epub 2016 Oct 24. Review. PubMed PMID: 27715344. 16: Rexer H, Retz M, Albers P. [Adjuvant study of high-risk muscle invasive urothelial carcinoma : Open-label, multicenter, randomized phase III study with atezolizumab (anti-PD-L1 antibody) as adjuvant therapy compared with observation in patients with high-risk muscle invasive urothelial carcinoma after surgical resection (IMvigor010)- study AB 53/15 of the AUO]. Urologe A. 2016 Nov;55(11):1491-1493. German. PubMed PMID: 27714413. 17: Luu C, Khushalani NI, Zager JS. Intralesional and systemic immunotherapy for metastatic melanoma. Expert Opin Biol Ther. 2016 Dec;16(12):1491-1499. Epub 2016 Sep 20. Review. PubMed PMID: 27602429. 18: Liu Y, Li L, Guo Q, Wang L, Liu D, Wei Z, Zhou J. Novel Cs-Based Upconversion Nanoparticles as Dual-Modal CT and UCL Imaging Agents for Chemo-Photothermal Synergistic Therapy. Theranostics. 2016 Jun 17;6(10):1491-505. doi: 10.7150/thno.15111. eCollection 2016. PubMed PMID: 27446485; PubMed Central PMCID: PMC4955050. 19: Chee J, Pang KW, Yong JM, Ho RC, Ngo R. Topical versus oral antibiotics, with or without corticosteroids, in the treatment of tympanostomy tube otorrhea. Int J Pediatr Otorhinolaryngol. 2016 Jul;86:183-8. doi: 10.1016/j.ijporl.2016.05.008. Epub 2016 May 11. PubMed PMID: 27260604. 20: Smolders EJ, Kanter CT, Grintjes K, D'Avolio A, Di Perri G, van Crevel R, Drenth JP, Burger DM. Sixty milligram daclatasvir is the right dose for hepatitis C virus treatment in combination with etravirine and darunavir/ritonavir. AIDS. 2016 Jun 1;30(9):1491-3. doi: 10.1097/QAD.0000000000001089. PubMed PMID: 27167014.