MedKoo Cat#: 591049 | Name: Add 4743

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Add 4743 is an analog of ciglitazone; adipogenic agent.

Chemical Structure

Add 4743
CAS#87858-57-9

Theoretical Analysis

MedKoo Cat#: 591049

Name: Add 4743

CAS#: 87858-57-9

Chemical Formula: C18H23NO4S

Exact Mass: 349.1348

Molecular Weight: 349.45

Elemental Analysis: C, 61.87; H, 6.63; N, 4.01; O, 18.31; S, 9.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Add 4743; Add4743; Add-4743
IUPAC/Chemical Name
2,4-Thiazolidinedione, 5-((4-((3-hydroxy-1-methylcyclohexyl)methoxy)phenyl)methyl)-
InChi Key
AVOKTXBQCWLDRM-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H23NO4S/c1-18(8-2-3-13(20)10-18)11-23-14-6-4-12(5-7-14)9-15-16(21)19-17(22)24-15/h4-7,13,15,20H,2-3,8-11H2,1H3,(H,19,21,22)
SMILES Code
O=C(N1)SC(CC2=CC=C(OCC3(C)CC(O)CCC3)C=C2)C1=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 349.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Orlicky DJ, Lieber JG, Morin CL, Evans RM. Synthesis and accumulation of a receptor regulatory protein associated with lipid droplet accumulation in 3T3-L1 cells. J Lipid Res. 1998 Jun;39(6):1152-61. PubMed PMID: 9643346. 2: Sparks RL, Strauss EE, Zygmunt AI, Phelan TE. Antidiabetic AD4743 enhances adipocyte differentiation of 3T3 T mesenchymal stem cells. J Cell Physiol. 1991 Jan;146(1):101-9. PubMed PMID: 1990013. 3: Hiragun A, Sato M, Mitsui H. Preadipocyte differentiation in vitro: identification of a highly active adipogenic agent. J Cell Physiol. 1988 Jan;134(1):124-30. PubMed PMID: 3275678.