MedKoo Cat#: 596091 | Name: Jaceidin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Jaceidin is an O-methylated flavonol. It can be found in Chamomilla recutita, and in Centaurea jacea.

Chemical Structure

Jaceidin
Jaceidin
CAS#10173-01-0

Theoretical Analysis

MedKoo Cat#: 596091

Name: Jaceidin

CAS#: 10173-01-0

Chemical Formula: C18H16O8

Exact Mass: 360.0845

Molecular Weight: 360.31

Elemental Analysis: C, 60.00; H, 4.48; O, 35.52

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Jaceidin;
IUPAC/Chemical Name
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxy-4H-chromen-4-one
InChi Key
XUWTZJRCCPNNJR-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H16O8/c1-23-11-6-8(4-5-9(11)19)16-18(25-3)15(22)13-12(26-16)7-10(20)17(24-2)14(13)21/h4-7,19-21H,1-3H3
SMILES Code
O=C1C(OC)=C(C2=CC=C(O)C(OC)=C2)OC3=CC(O)=C(OC)C(O)=C13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 360.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Allison BJ, Allenby MC, Bryant SS, Min JE, Hieromnimon M, Joyner PM. Antibacterial activity of fractions from three Chumash medicinal plant extracts and in vitro inhibition of the enzyme enoyl reductase by the flavonoid jaceosidin. Nat Prod Res. 2017 Mar;31(6):707-712. doi: 10.1080/14786419.2016.1217201. Epub 2016 Aug 2. PubMed PMID: 27482826. 2: Tahtah Y, Wubshet SG, Kongstad KT, Heskes AM, Pateraki I, Møller BL, Jäger AK, Staerk D. High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography-high-resolution mass spectrometry-solid-phase extraction-nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida. Fitoterapia. 2016 Apr;110:52-8. doi: 10.1016/j.fitote.2016.02.008. Epub 2016 Feb 14. PubMed PMID: 26882973. 3: Taamalli A, Arráez-Román D, Abaza L, Iswaldi I, Fernández-Gutiérrez A, Zarrouk M, Segura-Carretero A. LC-MS-based metabolite profiling of methanolic extracts from the medicinal and aromatic species Mentha pulegium and Origanum majorana. Phytochem Anal. 2015 Sep-Oct;26(5):320-30. doi: 10.1002/pca.2566. Epub 2015 May 15. PubMed PMID: 25982347. 4: Kanazawa K, Hashimoto T, Yoshida S, Sungwon P, Fukuda S. Short photoirradiation induces flavonoid synthesis and increases its production in postharvest vegetables. J Agric Food Chem. 2012 May 2;60(17):4359-68. doi: 10.1021/jf300107s. Epub 2012 Apr 20. PubMed PMID: 22506664. 5: Aljancić I, Stanković M, Tesević V, Vujisić L, Vajs V, Milosavljević S. Protective effect on human lymphocytes of some flavonoids isolated from two Achillea species. Nat Prod Commun. 2010 May;5(5):729-32. PubMed PMID: 20521537. 6: Hussain J, Khan FU, Ur Rehman N, Ullah R, Mohmmad Z, Tasleem S, Naeem A, Shah MR. One new triterpene ester from Nepeta suavis. J Asian Nat Prod Res. 2009 Dec;11(12):997-1000. doi: 10.1080/10286020903264085. PubMed PMID: 20183267. 7: Afifi FU, Aburjai T. Antiplatelet activity of Varthemia iphionoides. Fitoterapia. 2004 Dec;75(7-8):629-33. PubMed PMID: 15567236. 8: Long C, Sauleau P, David B, Lavaud C, Cassabois V, Ausseil F, Massiot G. Bioactive flavonoids of Tanacetum parthenium revisited. Phytochemistry. 2003 Sep;64(2):567-9. PubMed PMID: 12943776. 9: Fukui K, Matsumoto T, Nakamura S, Nakayama M, Horie T. The synthesis of jaceidin. Experientia. 1968 Feb 15;24(2):108-9. PubMed PMID: 5643784.