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MedKoo Cat#: 591017 | Name: Acridine-3,6-diol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Acridine-3,6-diol is a dye chemical.

Chemical Structure

Acridine-3,6-diol
CAS#43129-74-4

Theoretical Analysis

MedKoo Cat#: 591017

Name: Acridine-3,6-diol

CAS#: 43129-74-4

Chemical Formula: C13H9NO2

Exact Mass: 211.0633

Molecular Weight: 211.20

Elemental Analysis: C, 73.92; H, 4.30; N, 6.63; O, 15.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Acridine-3,6-diol;
IUPAC/Chemical Name
Acridine-3,6-diol
InChi Key
LXFYIIKDJZNGST-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H9NO2/c15-10-3-1-8-5-9-2-4-11(16)7-13(9)14-12(8)6-10/h1-7,15-16H
SMILES Code
OC1=CC2=NC3=CC(O)=CC=C3C=C2C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 211.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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PubMed PMID: 29755557; PubMed Central PMCID: PMC5937096. 4: Mohammadi P, Hassani Bafrani H, Tavalaee M, Dattilo M, Nasr-Esfahani MH. One-carbon cycle support rescues sperm damages in experimentally induced varicocele in rats. BJU Int. 2018 May 11. doi: 10.1111/bju.14385. [Epub ahead of print] PubMed PMID: 29752770. 5: Patnaik R, Padhy RN. Comparative study on toxicity of methylmercury chloride and methylmercury hydroxide to the human neuroblastoma cell line SH-SY5Y. Environ Sci Pollut Res Int. 2018 May 11. doi: 10.1007/s11356-018-2164-2. [Epub ahead of print] PubMed PMID: 29752667. 6: Zheng Y, Zheng Z, Ming Y, Lin M, Chen L, Huang W, Xiao J, Lin H. Gynosaponin TN-1 producing from the enzymatic conversion of gypenoside XLVI by naringinase and its cytotoxicity on hepatoma cell lines. Food Chem Toxicol. 2018 May 8. pii: S0278-6915(18)30297-7. doi: 10.1016/j.fct.2018.05.007. [Epub ahead of print] PubMed PMID: 29751078. 7: Liu S, Li X, Li Q, Liu H, Shi Y, Zhuo H, Li C, Zhu H. Silencing Livin improved the sensitivity of colon cancer cells to 5-fluorouracil by regulating crosstalk between apoptosis and autophagy. Oncol Lett. 2018 May;15(5):7707-7715. doi: 10.3892/ol.2018.8282. Epub 2018 Mar 16. PubMed PMID: 29740490; PubMed Central PMCID: PMC5934728. 8: Zhou Q, You C, Zheng C, Gu Y, Gu H, Zhang R, Wu H, Sun B. 3-Nitroacridine derivatives arrest cell cycle at G0/G1 phase and induce apoptosis in human breast cancer cells may act as DNA-target anticancer agents. Life Sci. 2018 May 5. pii: S0024-3205(18)30250-9. doi: 10.1016/j.lfs.2018.05.010. [Epub ahead of print] PubMed PMID: 29738780. 9: Sudha A, Srinivasan P, Kanimozhi V, Palanivel K, Kadalmani B. Antiproliferative and apoptosis-induction studies of 5-hydroxy 3',4',7-trimethoxyflavone in human breast cancer cells MCF-7: an in vitro and in silico approach. J Recept Signal Transduct Res. 2018 May 8:1-12. doi: 10.1080/10799893.2018.1468780. [Epub ahead of print] PubMed PMID: 29734849. 10: Almeida D, Pinho R, Correia V, Soares J, Bastos ML, Carvalho F, Capela JP, Costa VM. Mitoxantrone is More Toxic than Doxorubicin in SH-SY5Y Human Cells: A 'Chemobrain' In Vitro Study. Pharmaceuticals (Basel). 2018 May 5;11(2). pii: E41. doi: 10.3390/ph11020041. PubMed PMID: 29734752. 11: Yang HB, Gao HR, Ren YJ, Fang FX, Tian HT, Gao ZJ, Song W, Huang SM, Zhao AF. Effects of isoimperatorin on proliferation and apoptosis of human gastric carcinoma cells. Oncol Lett. 2018 May;15(5):7993-7998. doi: 10.3892/ol.2018.8303. Epub 2018 Mar 20. PubMed PMID: 29731910; PubMed Central PMCID: PMC5920862. 12: Jaafaru MS, Nordin N, Shaari K, Rosli R, Abdull Razis AF. Isothiocyanate from Moringa oleifera seeds mitigates hydrogen peroxide-induced cytotoxicity and preserved morphological features of human neuronal cells. PLoS One. 2018 May 3;13(5):e0196403. doi: 10.1371/journal.pone.0196403. eCollection 2018. PubMed PMID: 29723199. 13: Želježić D, Žunec S, Bjeliš M, Benković V, Mladinić M, Lovaković Tariba B, Pavičić I, Marjanović Čermak AM, Kašuba V, Milić M, Pizent A, Lucić Vrdoljak A, Kopjar N. Effects of the chloro-s-triazine herbicide terbuthylazine on DNA integrity in human and mouse cells. Environ Sci Pollut Res Int. 2018 May 2. doi: 10.1007/s11356-018-2046-7. [Epub ahead of print] PubMed PMID: 29721798. 14: Cheng SY, Chen NF, Kuo HM, Yang SN, Sung CS, Sung PJ, Wen ZH, Chen WF. Prodigiosin stimulates endoplasmic reticulum stress and induces autophagic cell death in glioblastoma cells. Apoptosis. 2018 May 2. doi: 10.1007/s10495-018-1456-9. [Epub ahead of print] PubMed PMID: 29721785. 15: Zhou Y, Quan G, Wu Q, Zhang X, Niu B, Wu B, Huang Y, Pan X, Wu C. Mesoporous silica nanoparticles for drug and gene delivery. Acta Pharm Sin B. 2018 Mar;8(2):165-177. doi: 10.1016/j.apsb.2018.01.007. Epub 2018 Feb 12. Review. PubMed PMID: 29719777; PubMed Central PMCID: PMC5926503. 16: Hsiao YT, Kuo CL, Lin JJ, Huang WW, Peng SF, Chueh FS, Bau DT, Chung JG. Curcuminoids combined with gefitinib mediated apoptosis and autophagy of human oral cancer SAS cells in vitro and reduced tumor of SAS cell xenograft mice in vivo. Environ Toxicol. 2018 May 2. doi: 10.1002/tox.22568. [Epub ahead of print] PubMed PMID: 29717538. 17: Golec B, Nawara K, Gorski A, Thummel RP, Herbich J, Waluk J. Combined effect of hydrogen bonding interactions and freezing of rotameric equilibrium on the enhancement of photostability. Phys Chem Chem Phys. 2018 May 16;20(19):13306-13315. doi: 10.1039/c8cp00726h. PubMed PMID: 29717306. 18: Forberg D, Schwob T, Kempe R. Catalytic condensation for the formation of polycyclic heteroaromatic compounds. Nat Commun. 2018 May 1;9(1):1751. doi: 10.1038/s41467-018-04143-6. PubMed PMID: 29717125; PubMed Central PMCID: PMC5931520. 19: Panner Selvam MK, Agarwal A. 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Acetoxy AAF

Acetoxy AAF