MedKoo Cat#: 591011 | Name: Acridine Yellow

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Acridine yellow, also known as acridine yellow G, acridine yellow H107, basic yellow K, and 3,6-diamino-2,7-dimethylacridine, is a yellow dye with strong bluish-green fluorescence.

Chemical Structure

Acridine Yellow
CAS#92-26-2

Theoretical Analysis

MedKoo Cat#: 591011

Name: Acridine Yellow

CAS#: 92-26-2

Chemical Formula: C15H15N3

Exact Mass: 237.1266

Molecular Weight: 237.31

Elemental Analysis: C, 75.92; H, 6.37; N, 17.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Acridine Yellow Base;
IUPAC/Chemical Name
2,7-Dimethylacridine-3,6-diamine
InChi Key
HGHJYCKSBMCGRK-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H15N3/c1-8-3-10-5-11-4-9(2)13(17)7-15(11)18-14(10)6-12(8)16/h3-7H,16-17H2,1-2H3
SMILES Code
NC1=CC2=NC3=CC(N)=C(C)C=C3C=C2C=C1C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 237.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Westergaard Mulberg M, Taskova M, Thomsen RP, Okholm AH, Kjems J, Astakhova K. New Fluorescent Nanoparticles for Ultrasensitive Detection of Nucleic Acids by Optical Methods. Chembiochem. 2017 Aug 17;18(16):1599-1603. doi: 10.1002/cbic.201700125. Epub 2017 Jul 6. PubMed PMID: 28681411. 2: Calahorra M, Sánchez NS, Peña A. Acridine yellow. A novel use to estimate and measure the plasma membrane potential in Saccharomyces cerevisiae. J Bioenerg Biomembr. 2017 Jun;49(3):281-290. doi: 10.1007/s10863-017-9699-7. Epub 2017 Mar 31. PubMed PMID: 28364383. 3: Mitra P, Chakraborty PK, Saha P, Ray P, Basu S. Antibacterial efficacy of acridine derivatives conjugated with gold nanoparticles. Int J Pharm. 2014 Oct 1;473(1-2):636-43. doi: 10.1016/j.ijpharm.2014.07.051. Epub 2014 Aug 1. PubMed PMID: 25087507. 4: Heras-Ojea MJ, Mañeru DR, Rosado L, Zuazo JR, Castro GR, Tewary S, Rajaraman G, Aromí G, Jiménez E, Sañudo EC. Characterization of a robust co(II) fluorescent complex deposited intact on HOPG. Chemistry. 2014 Aug 11;20(33):10439-45. doi: 10.1002/chem.201402814. Epub 2014 Jul 2. PubMed PMID: 24989818. 5: Abolhasani J, Hassanzadeh J. Potassium permanganate-acridine yellow chemiluminescence system for the determination of fluvoxamine, isoniazid and ceftriaxone. Luminescence. 2014 Dec;29(8):1053-8. doi: 10.1002/bio.2659. Epub 2014 Apr 22. PubMed PMID: 24753178. 6: Herb JT, Anderson BD. Investigating the binding of acridine, acridine orange, and acridine yellow G to humic acid through fluorescence quenching. Appl Spectrosc. 2013 Jul;67(7):752-6. doi: 10.1366/12-06795. PubMed PMID: 23816127. 7: Aidas K, Olsen JM, Kongsted J, Ågren H. Photoabsorption of acridine yellow and proflavin bound to human serum albumin studied by means of quantum mechanics/molecular dynamics. J Phys Chem B. 2013 Feb 21;117(7):2069-80. doi: 10.1021/jp311863x. Epub 2013 Feb 6. PubMed PMID: 23356863. 8: Qi Q, He K, Yoo MH, Chan CB, Liu X, Zhang Z, Olson JJ, Xiao G, Wang L, Mao H, Fu H, Tao H, Ramalingam SS, Sun SY, Mischel PS, Ye K. Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases. J Biol Chem. 2012 Feb 24;287(9):6113-27. doi: 10.1074/jbc.M111.293605. Epub 2012 Jan 3. PubMed PMID: 22215664; PubMed Central PMCID: PMC3307261. 9: Zong W, Cao S, Xu Q, Liu R. The use of outer filter effects for Cu(2+) quantitation: a unique example for monitoring nonfluorescent molecule with fluorescence. Luminescence. 2012 Jul-Aug;27(4):292-6. doi: 10.1002/bio.1349. Epub 2011 Oct 25. PubMed PMID: 22025485. 10: Saint-Cricq P, Pigot T, Blanc S, Lacombe S. Selective oxidation with nanoporous silica supported sensitizers: an environment friendly process using air and visible light. J Hazard Mater. 2012 Apr 15;211-212:266-74. doi: 10.1016/j.jhazmat.2011.09.066. Epub 2011 Oct 1. PubMed PMID: 22019105. 11: Chakraborty B, Roy AS, Dasgupta S, Basu S. Magnetic field effect corroborated with docking study to explore photoinduced electron transfer in drug-protein interaction. J Phys Chem A. 2010 Dec 30;114(51):13313-25. doi: 10.1021/jp109604a. Epub 2010 Dec 2. PubMed PMID: 21126029. 12: Long YF, Huang CZ, Li YF. Hybridization detection of DNA by measuring organic small molecule amplified resonance light scattering signals. J Phys Chem B. 2007 May 3;111(17):4535-8. Epub 2007 Apr 7. PubMed PMID: 17417892. 13: Feng S, Shi H. Spectroscopic study on the interaction of acridine yellow with adenosine disodium triphosphate and its analytical application. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Oct;68(2):244-9. Epub 2006 Nov 24. PubMed PMID: 17267271. 14: Aslan K, Malyn SN, Geddes CD. Fast and sensitive DNA hybridization assays using microwave-accelerated metal-enhanced fluorescence. Biochem Biophys Res Commun. 2006 Sep 22;348(2):612-7. Epub 2006 Jul 28. PubMed PMID: 16890197. 15: Liu SP, Sa C, Hu XL, Kong L. Fluorescence quenching method for the determination of sodium carboxymethyl cellulose with acridine yellow or acridine orange. Spectrochim Acta A Mol Biomol Spectrosc. 2006 Jul;64(4):817-22. Epub 2006 Feb 2. PubMed PMID: 16458058. 16: Si WH, Zi YQ. [Multi-wavelength negative absorption fading spectrophotometry to determine trace nitrite and it's mechanism]. Guang Pu Xue Yu Guang Pu Fen Xi. 2005 Oct;25(10):1671-3. Chinese. PubMed PMID: 16395910. 17: Michel KP, Berry S, Hifney A, Kruip J, Pistorius EK. Adaptation to iron deficiency: a comparison between the cyanobacterium Synechococcus elongatus PCC 7942 wild-type and a DpsA-free mutant. Photosynth Res. 2003;75(1):71-84. PubMed PMID: 16245095. 18: Berry S, Fischer JH, Kruip J, Hauser M, Wildner GF. Monitoring cytosolic pH of carboxysome-deficient cells of Synechocystis sp. PCC 6803 using fluorescence analysis. Plant Biol (Stuttg). 2005 Jul;7(4):342-7. PubMed PMID: 16025406. 19: Vetkin DO, Gaĭnullina ET, Karavaev VA, Nurmukhametov RN, Ryzhikov SB, Taranchenko VF. [Study of the cholinesterase active site using a fluorescent probe]. Izv Akad Nauk Ser Biol. 2004 Mar-Apr;(2):157-62. Russian. PubMed PMID: 15131977. 20: Ryu JY, Song JY, Lee JM, Jeong SW, Chow WS, Choi SB, Pogson BJ, Park YI. Glucose-induced expression of carotenoid biosynthesis genes in the dark is mediated by cytosolic ph in the cyanobacterium Synechocystis sp. PCC 6803. J Biol Chem. 2004 Jun 11;279(24):25320-5. Epub 2004 Apr 12. PubMed PMID: 15078876.