MedKoo Cat#: 562721 | Name: Texasin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Texasin is a selective human leukocyte 5-lipoxygenase (5-LOX) inhibitor.

Chemical Structure

Texasin
CAS#897-46-1

Theoretical Analysis

MedKoo Cat#: 562721

Name: Texasin

CAS#: 897-46-1

Chemical Formula: C16H12O5

Exact Mass: 284.0685

Molecular Weight: 284.26

Elemental Analysis: C, 67.60; H, 4.26; O, 28.14

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Texasin; IR-2; IR 2; IR2;
IUPAC/Chemical Name
6,7-Dihydroxy-3-(4-methoxyphenyl)-4-benzopyrone
InChi Key
GCWOYVFHJDNKIN-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H12O5/c1-20-10-4-2-9(3-5-10)12-8-21-15-7-14(18)13(17)6-11(15)16(12)19/h2-8,17-18H,1H3
SMILES Code
O=C1C(C2=CC=C(OC)C=C2)=COC3=CC(O)=C(O)C=C13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 284.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sun XD, Fang SM, Zang MD, Yang CX, Li HR, Kitanaka S, Yang XD. [Isoflavonoids from Caragana changduensis and their nitric oxideinhibitory activities]. Zhongguo Zhong Yao Za Zhi. 2015 Aug;40(16):3220-3. Chinese. PubMed PMID: 26790296. 2: Lu TM, Ko HH, Ng LT, Hsieh YP. Free-Radical-Scavenging, Antityrosinase, and Cellular Melanogenesis Inhibitory Activities of Synthetic Isoflavones. Chem Biodivers. 2015 Jun;12(6):963-79. doi: 10.1002/cbdv.201400208. PubMed PMID: 26080742. 3: Mascayano C, Espinosa V, Sepúlveda-Boza S, Hoobler EK, Perry S, Diaz G, Holman TR. Enzymatic Studies of Isoflavonoids as Selective and Potent Inhibitors of Human Leukocyte 5-Lipo-Oxygenase. Chem Biol Drug Des. 2015 Jul;86(1):114-21. doi: 10.1111/cbdd.12469. Epub 2014 Nov 28. PubMed PMID: 25359714. 4: Kim JM, Ko RK, Jung DS, Kim SS, Lee NH. Tyrosinase inhibitory constituents from the stems of Maackia fauriei. Phytother Res. 2010 Jan;24(1):70-5. doi: 10.1002/ptr.2870. PubMed PMID: 19441007. 5: Klejdus B, Vacek J, Benesová L, Kopecký J, Lapcík O, Kubán V. Rapid-resolution HPLC with spectrometric detection for the determination and identification of isoflavones in soy preparations and plant extracts. Anal Bioanal Chem. 2007 Dec;389(7-8):2277-85. Epub 2007 Sep 26. PubMed PMID: 17899029. 6: Poulton JE, Kauer M. Identification of an UDP-glucose: Flavonol 3-O-glucosyl-transferase from cell suspension cultures of soybean (Glycine max L.). Planta. 1977 Jan;136(1):53-9. doi: 10.1007/BF00387925. PubMed PMID: 24420227.