MedKoo Cat#: 562716 | Name: WAY-260022

Description:

WARNING: This product is for research use only, not for human or veterinary use.

WAY-260022 is a selective inhibitor of the norepinephrine transporter.

Chemical Structure

WAY-260022
WAY-260022
CAS#850692-43-2

Theoretical Analysis

MedKoo Cat#: 562716

Name: WAY-260022

CAS#: 850692-43-2

Chemical Formula: C21H31F3N2O2

Exact Mass: 400.2338

Molecular Weight: 400.48

Elemental Analysis: C, 62.98; H, 7.80; F, 14.23; N, 6.99; O, 7.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
WAY-260022; WAY 260022; WAY260022; NRI-022; NRI 022; NRI022;
IUPAC/Chemical Name
1-[(1S)-2-[(3S,5R)-3,5-Dimethylpiperazin-1-yl]-1-[3-(trifluoromethoxy)phenyl]ethyl]cyclohexan-1-ol
InChi Key
ZNDZJNVJUAKEQC-JTDSTZFVSA-N
InChi Code
InChI=1S/C21H31F3N2O2/c1-15-12-26(13-16(2)25-15)14-19(20(27)9-4-3-5-10-20)17-7-6-8-18(11-17)28-21(22,23)24/h6-8,11,15-16,19,25,27H,3-5,9-10,12-14H2,1-2H3/t15-,16+,19-/m1/s1
SMILES Code
OC1([C@@H](C2=CC=CC(OC(F)(F)F)=C2)CN3C[C@H](C)N[C@H](C)C3)CCCCC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 400.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Gavrin LK, Mahaney PE, Jenkins D, Nogle LM, Mugford CA, Huselton C, Leiter J, Johnston GH, Bray JA, Burroughs KD, Cosmi SA, Alfinito P, Ho DM, Deecher DC, Trybulski EJ. Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter. ACS Med Chem Lett. 2010 Mar 25;1(3):91-5. doi: 10.1021/ml100009p. eCollection 2010 Jun 10. PubMed PMID: 24900182; PubMed Central PMCID: PMC4007968.