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MedKoo Cat#: 562701 | Name: YH-306

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YH-306 is a modulator of the FAK signalling pathway. It acts by suppressing colorectal tumour growth and metastasis.

Chemical Structure

YH-306
YH-306
CAS#1373764-75-0

Theoretical Analysis

MedKoo Cat#: 562701

Name: YH-306

CAS#: 1373764-75-0

Chemical Formula: C19H18N2O2

Exact Mass: 306.1368

Molecular Weight: 306.36

Elemental Analysis: C, 74.49; H, 5.92; N, 9.14; O, 10.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
YH-306; YH 306; YH306;
IUPAC/Chemical Name
2-(4-Hydroxyphenyl)-1-(1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-ethanone
InChi Key
WFTJZQLEQGPZBC-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H18N2O2/c22-14-7-5-13(6-8-14)11-19(23)21-10-9-16-15-3-1-2-4-17(15)20-18(16)12-21/h1-8,20,22H,9-12H2
SMILES Code
OC1=CC=C(CC(N(C2)CCC3=C2NC4=C3C=CC=C4)=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 306.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Dai F, Chen Y, Huang L, Wang J, Zhang T, Li J, Tong W, Liu M, Yi Z. A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. J Cell Mol Med. 2015 Feb;19(2):383-95. doi: 10.1111/jcmm.12450. Epub 2014 Oct 29. PubMed PMID: 25351103; PubMed Central PMCID: PMC4407606.