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MedKoo Cat#: 562700 | Name: MS437

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS437 is a potent agonist of the TSH receptor (TSHR).

Chemical Structure

MS437
MS437
CAS#541535-31-3

Theoretical Analysis

MedKoo Cat#: 562700

Name: MS437

CAS#: 541535-31-3

Chemical Formula: C22H24N2O

Exact Mass: 332.1889

Molecular Weight: 332.44

Elemental Analysis: C, 79.48; H, 7.28; N, 8.43; O, 4.81

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MS437; MS-437; MS 437;
IUPAC/Chemical Name
N,N-diisopropyl-2-phenylquinoline-4-carboxamide
InChi Key
LXECNSUVDZQPHW-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H24N2O/c1-15(2)24(16(3)4)22(25)19-14-21(17-10-6-5-7-11-17)23-20-13-9-8-12-18(19)20/h5-16H,1-4H3
SMILES Code
O=C(N(C(C)C)C(C)C)C1=C2C(C=CC=C2)=NC(C3=CC=CC=C3)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 332.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Latif R, Ali MR, Ma R, David M, Morshed SA, Ohlmeyer M, Felsenfeld DP, Lau Z, Mezei M, Davies TF. New small molecule agonists to the thyrotropin receptor. Thyroid. 2015 Jan;25(1):51-62. doi: 10.1089/thy.2014.0119. PubMed PMID: 25333622; PubMed Central PMCID: PMC4291085.