MedKoo Cat#: 596022 | Name: AL-8417

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AL-8417 is an enzyme inhibitor. It also has the ability to suppress vitrectomy-induced posterior lens fiber changes, acting as antioxidant, anti-inflammatory and cytostatic agent.

Chemical Structure

AL-8417
AL-8417
CAS#180472-20-2

Theoretical Analysis

MedKoo Cat#: 596022

Name: AL-8417

CAS#: 180472-20-2

Chemical Formula: C29H34O5

Exact Mass: 462.2406

Molecular Weight: 462.58

Elemental Analysis: C, 75.30; H, 7.41; O, 17.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
AL-8417; (2R)-AL-5898; J1.090.276B; AL8417; AL 8417;
IUPAC/Chemical Name
2-((R)-6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)ethyl (S)-2-(6-methoxynaphthalen-2-yl)propanoate
InChi Key
KYECYAFVFZRXIM-ADXZGYQBSA-N
InChi Code
InChI=1S/C29H34O5/c1-17-18(2)27-25(20(4)26(17)30)11-12-29(5,34-27)13-14-33-28(31)19(3)21-7-8-23-16-24(32-6)10-9-22(23)15-21/h7-10,15-16,19,30H,11-14H2,1-6H3/t19-,29+/m0/s1
SMILES Code
O=C(OCC[C@@]1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)[C@@H](C)C3=CC=C4C=C(OC)C=CC4=C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 462.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: David KC, Brady MT, Weimer LK, Hellberg MR, Nixon JC, Graff G. Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides. Inflammation. 2003 Feb;27(1):31-43. PubMed PMID: 12772775. 2: Kuszak JR, Sivak JG, Moran KL, Scheib SA, Garner WH, Ke TL, Hellberg MR, Graff G. Suppression of post-vitrectomy lens changes in the rabbit by novel benzopyranyl esters and amides. Exp Eye Res. 2002 Oct;75(4):459-73. PubMed PMID: 12387793.