Propargyl-PEG4-Maleimide is a PEG derivative containing a propargyl group and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal alkyne will react with azides via copper-catalyzed Click Chemistry. PEG Linkers are useful for the development of antibody drug conjugates.
MedKoo Cat#: 571715
Name: Propargyl-PEG4-Maleimide
CAS#: 1609651-90-2
Chemical Formula: C18H26N2O7
Exact Mass: 382.1740
Molecular Weight: 382.41
Elemental Analysis: C, 56.54; H, 6.85; N, 7.33; O, 29.29
The following data is based on the product molecular weight 382.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
