MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 562687 | Name: TPI-1917-49

Description:

WARNING: This product is for research use only, not for human or veterinary use.

TPI-1917-49 is a promising amyloid reducing agent that acts by lowering the levels of Aβ.

Chemical Structure

TPI-1917-49
TPI-1917-49
CAS#1250849-11-6

Theoretical Analysis

MedKoo Cat#: 562687

Name: TPI-1917-49

CAS#: 1250849-11-6

Chemical Formula: C29H26N6O3S2

Exact Mass: 570.1508

Molecular Weight: 570.68

Elemental Analysis: C, 61.04; H, 4.59; N, 14.73; O, 8.41; S, 11.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
TPI-1917-49; TPI 1917 49; TPI191749;
IUPAC/Chemical Name
3-[[4-(3-Hydroxyphenyl)-2-thiazolyl]amino]-4-[4-[4-(3-hydroxyphenyl)-2-thiazolyl]-1-piperazinyl]-benzamide
InChi Key
CZZOAECTXWFUKT-UHFFFAOYSA-N
InChi Code
InChI=1S/C29H26N6O3S2/c30-27(38)20-7-8-26(23(15-20)31-28-32-24(16-39-28)18-3-1-5-21(36)13-18)34-9-11-35(12-10-34)29-33-25(17-40-29)19-4-2-6-22(37)14-19/h1-8,13-17,36-37H,9-12H2,(H2,30,38)(H,31,32)
SMILES Code
O=C(N)C1=CC=C(N2CCN(C3=NC(C4=CC=CC(O)=C4)=CS3)CC2)C(NC5=NC(C6=CC=CC(O)=C6)=CS5)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 570.68 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang H, Wang R, Lakshmana MK, Nefzi A. Substituted dithiazole piperazine benzamides as novel amyloid beta peptide reducing agents. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4384-4388. doi: 10.1016/j.bmcl.2014.08.022. Epub 2014 Aug 13. PubMed PMID: 25155386; PubMed Central PMCID: PMC4311522.