Propargyl-PEG9-bromide is a PEG derivative containing a propargyl group and a bromide group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. PEG Linkers are useful in the development of antibody drug conjugates.
MedKoo Cat#: 571713
Name: Propargyl-PEG9-bromide
CAS#: 2055042-83-4
Chemical Formula: C21H39BrO9
Exact Mass: 514.1777
Molecular Weight: 515.44
Elemental Analysis: C, 48.94; H, 7.63; Br, 15.50; O, 27.94
The following data is based on the product molecular weight 515.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
