Synonym
Amarsan; Amoebal; Osarsol; Vagisept; NSC 13160; NSC-13160; NSC13160.
IUPAC/Chemical Name
m-Arsanilic acid, N-acetyl-4-hydroxy-
InChi Key
ODFJOVXVLFUVNQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)
SMILES Code
O[As](O)(C1=CC=C(O)C(NC(C)=O)=C1)=O
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
275.09
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Olavarría-Fullerton J, Wells S, Ortiz-Rivera W, Sepaniak MJ, De Jesús MA. Surface-enhanced Raman scattering (SERS) characterization of trace organoarsenic antimicrobials using silver/polydimethylsiloxane nanocomposites. Appl Spectrosc. 2011 Apr;65(4):423-8. doi: 10.1366/10-06116. PubMed PMID: 21396190.
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5: WHITE A. Acute systemic reaction to acetarsol. Br Med J. 1956 Dec 29;2(5008):1528-9. PubMed PMID: 13374373; PubMed Central PMCID: PMC2036064.
6: SHVARTSVASSER IP, VAINGRIB LG. [Acute hemorrhagic encephalitis following intake of osarsol]. Sov Med. 1956 May;20(5):76-7. Russian. PubMed PMID: 13351919.
7: OEHNINGER C, RODRIGUEZ BARRIOS R, GOMEZ HAEDO CA. Optic neuritis caused by arsenicals; treatment with B.A.L. Br J Ophthalmol. 1955 Jul;39(7):422-8. PubMed PMID: 13240036; PubMed Central PMCID: PMC1324567.
8: BASCH. [Treatment of recurrent trichomonal vulvovaginitis by local applications of sodium stovarsol]. C R Soc Fr Gyncol. 1955 May-Sep;25(5):220-1. French. PubMed PMID: 13261526.
9: LEBON J, MESSERSCHMITT J. [Drug-induced aplastic myelosis; terminal acute myeloblstosis; pathogenic reflections]. Sang. 1955;26(8):799-804. French. PubMed PMID: 13337079.
10: BIERICH JR. [Spirocid encephalitis]. Arch Kinderheilkd. 1955;151(1):5-19. German. PubMed PMID: 13259600.
11: PECK BJ. Exfoliative dermatitis after acetarsol vaginal pessaries. Br Med J. 1954 Oct 9;2(4892):850-1. PubMed PMID: 13199327; PubMed Central PMCID: PMC2079486.
12: ANDRE L, MARTY J, RISPE R, MORICHAU-BEAUCHANT J. [Lymphoid leukemia in a syphilitic treated with sodium stovarsol and with bismuth]. Bull Mem Soc Med Hop Paris. 1954 May 14-21;70(15-16):540-3. French. PubMed PMID: 13190396.
13: JEDLICKA J. [Sarcoidosis pulmonum; a contribution to the chemotherapy of Besnier-Boeck-Schaumann disease. II. Report]. Sb Lek. 1954 Apr;56(4):73-8. Czech. PubMed PMID: 13237896.
14: KOSTIC P, GRUBAC M. [Not Available]. Med Glas. 1954 Mar-Apr;8(3-4):120-5. Undetermined Language. PubMed PMID: 13193381.
15: WATTLEY GH. The treatment of stovarsol-resistant balantidiasis with aureomycin; a case report. Caribb Med J. 1953;15(3-4):92-4. PubMed PMID: 13141256.
16: McCAREY AG. Balantidiasis in South Persia. Br Med J. 1952 Mar 22;1(4759):629-31. PubMed PMID: 14905008; PubMed Central PMCID: PMC2023172.
17: SONNECK HJ. [Erythematosus discoides chronicus with exacerbation by spirocid]. Dtsch Gesundheitsw. 1952 Feb 21;7(8):239-44. Undetermined Language. PubMed PMID: 14936556.
18: POPOVIC S. [Treatment of a case of poisoning with stovarsol with BAL]. Med Arh. 1952 Jan-Feb;6(1):55-62. Undetermined Language. PubMed PMID: 14947473.
19: OULES J, ALLAIX D. [Experimental stovarsol therapy of manic crises]. Ann Med Psychol (Paris). 1952 Jan;110(1 1):86-8. Undetermined Language. PubMed PMID: 14944008.
20: ORCHARD WE. Dermatitis after use of pentavalent arsenicals per vaginam. Br Med J. 1951 Dec 15;2(4745):1444. PubMed PMID: 14879130; PubMed Central PMCID: PMC2070664.
