Enkephalin | CAS# 74080-62-9| Opiod Growth Factor

MedKoo Cat#: 571545 | Name: Enkephalin-met, acetaldehyde-

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Enkephalin-met, acetaldehyde- serves to modulate the growth of human colon cancer and is a naturally occurring opioid peptide acts as a potent negative regulator of human gastrointestinal cancer and may suggest pathways for tumor etiology, progression, treatment, and prophylaxis.

Chemical Structure

Enkephalin-met, acetaldehyde-

CAS#74080-62-9

Theoretical Analysis

MedKoo Cat#: 571545

Name: Enkephalin-met, acetaldehyde-

CAS#: 74080-62-9

Chemical Formula: C29H37N5O7S

Exact Mass: 599.2400

Molecular Weight: 0.00

Elemental Analysis: C, 58.08; H, 6.22; N, 11.68; O, 18.67; S, 5.35

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Acetaldehyde-met-enkephalin; Methionine-enkephalin, acetaldehyde; Met-enkephalin, acetaldehyde

IUPAC/Chemical Name

L-Methionine, N-(N-(N-((4-((4-hydroxyphenyl)methyl)-2-methyl-5-oxo-1-imidazolidinyl)acetyl)glycyl)-L-phenylalanyl)-

InChi Key

GVZPFSIGGIAFFF-PRRLZWHQSA-N

InChi Code

InChI=1S/C29H37N5O7S/c1-18-31-24(15-20-8-10-21(35)11-9-20)28(39)34(18)17-26(37)30-16-25(36)32-23(14-19-6-4-3-5-7-19)27(38)33-22(29(40)41)12-13-42-2/h3-11,18,22-24,31,35H,12-17H2,1-2H3,(H,30,37)(H,32,36)(H,33,38)(H,40,41)/t18?,22-,23-,24?/m0/s1

SMILES Code

CSCC[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC(CNC(CN(C(C)NC2CC3=CC=C(O)C=C3)C2=O)=O)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 0.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Summers MC, Lightman SL. A reaction of acetaldehyde with enkephalins and related peptides. Biochem Pharmacol. 1981 Jun 15;30(12):1621-7. PubMed PMID: 6268105. 2: Summers MC, Hayes RJ. Acetaldehyde-enkephalins: pronounced changes in the opiate activity of methionine-enkephalin and leucine-enkephalin on reaction with acetaldehyde. FEBS Lett. 1980 Apr 21;113(1):99-101. PubMed PMID: 6247206. 3: Summers MC, Gidley MJ, Sanders JK. 'Acetaldehyde-enkephalins': elucidation of the structure of the acetaldehyde adducts of methionine-enkephalin and leucine-enkephalin. FEBS Lett. 1980 Mar 10;111(2):307-10. PubMed PMID: 7358173.