KM-233 | CAS#628263-22-9 | cannabinoid ligand

MedKoo Cat#: 562650 | Name: KM-233

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KM-233 is a cannabinoid ligand.

Chemical Structure

KM-233

CAS#628263-22-9

Theoretical Analysis

MedKoo Cat#: 562650

Name: KM-233

CAS#: 628263-22-9

Chemical Formula: C25H30O2

Exact Mass: 362.2246

Molecular Weight: 362.51

Elemental Analysis: C, 82.83; H, 8.34; O, 8.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

KM-233; KM 233; KM233;

IUPAC/Chemical Name

(6aR,10aR)-6,6,9-Trimethyl-3-(2-phenylpropan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol

InChi Key

GZYXCXRHVALIJD-WOJBJXKFSA-N

InChi Code

InChI=1S/C25H30O2/c1-16-11-12-20-19(13-16)23-21(26)14-18(15-22(23)27-25(20,4)5)24(2,3)17-9-7-6-8-10-17/h6-11,14-15,19-20,26H,12-13H2,1-5H3/t19-,20-/m1/s1

SMILES Code

OC1=CC(C(C)(C2=CC=CC=C2)C)=CC3=C1[C@@](CC(C)=CC4)([H])[C@]4([H])C(C)(C)O3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 362.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Gurley SN, Abidi AH, Allison P, Guan P, Duntsch C, Robertson JH, Kosanke SD, Keir ST, Bigner DD, Elberger AJ, Moore BM 2nd. Mechanism of anti-glioma activity and in vivo efficacy of the cannabinoid ligand KM-233. J Neurooncol. 2012 Nov;110(2):163-77. doi: 10.1007/s11060-012-0958-5. Epub 2012 Aug 9. PubMed PMID: 22875710. 2: Duntsch C, Divi MK, Jones T, Zhou Q, Krishnamurthy M, Boehm P, Wood G, Sills A, Moore BM 2nd. Safety and efficacy of a novel cannabinoid chemotherapeutic, KM-233, for the treatment of high-grade glioma. J Neurooncol. 2006 Apr;77(2):143-52. Epub 2005 Nov 29. PubMed PMID: 16314952. 3: Mason WT Jr. A survey of benthic invertebrates in the Suwannee River, Florida. Environ Monit Assess. 1991 Feb;16(2):163-87. doi: 10.1007/BF00418103. PubMed PMID: 24241891.