MedKoo Cat#: 581221 | Name: Daeatal

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Dynorphin A ethylamide (1-9), The opioid activities were examined in the bioassays (guinea pig ileum, mouse vas deferens and rabbit vas deferens). the extension of the C-terminal in the peptide chain of [MeArg7,D-Leu8]-Dyn(1-8)-NH2 analogues by Arg is ineffective for increasing the kappa-opioid activities, kappa-receptor selectivity and/or analgesic effects of the peptides.

Chemical Structure

Daeatal
Daeatal
CAS#103614-28-4

Theoretical Analysis

MedKoo Cat#: 581221

Name: Daeatal

CAS#: 103614-28-4

Chemical Formula: C32H43N5O6

Exact Mass: 593.3213

Molecular Weight: 593.73

Elemental Analysis: C, 64.74; H, 7.30; N, 11.80; O, 16.17

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Synonym
Daeatal; Dynorphin A ethylamide (1-9), metyr(1)-mearg(7)-leu(8)-;
IUPAC/Chemical Name
1-Metyr-7-mearg-8-leu-dynorphin (1-9)-nhet
InChi Key
UCENISLVVUEBDB-FYWRMAATSA-N
InChi Code
InChI=1S/C32H43N5O6/c1-19(2)27(36-29(38)20(3)33-4)32(41)37-16-14-26-28(37)31(40)35-24(17-21-9-7-6-8-10-21)30(39)34-15-13-22-18-23(43-26)11-12-25(22)42-5/h6-13,15,19-20,22,24,26-28,33H,14,16-18H2,1-5H3,(H,34,39)(H,35,40)(H,36,38)/b15-13+
SMILES Code
CC(NC)C(NC(C(N1CCC(C1C(NC2CC3=CC=CC=C3)=O)OC(C4)=CC=C(OC)C4/C=C/NC2=O)=O)C(C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 593.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Yoshino H, Arakawa Y, Nakazawa T, Kaneko T, Matsunaga M, Araki S, Ikeda M, Tsuchiya Y, Yamatsu K, Tachibana S. Synthesis and biological activity of [MeTyr1,MeArg7,D-Leu8]-dynorphin A(1-9)-NHEt and [D-Cys2-Cys5,MeArg7,D-Leu8]-dynorphin A(1-9)-NH2. Chem Pharm Bull (Tokyo). 1990 Aug;38(8):2274-6. PubMed PMID: 1980641.