Wee1 Inhibitor II is a small-molecule inhibitor that selectively targets the Wee1 kinase, a key regulator of the G2/M checkpoint in the cell cycle. By inhibiting Wee1, it disrupts DNA damage repair and induces mitotic entry, making it a potential tool for studying cancer cell cycle regulation and sensitizing tumor cells to DNA-damaging agents. Its mechanism of action highlights its relevance in cancer research, particularly in exploring synthetic lethality approaches.
MedKoo Cat#: 562589
Name: Wee1 Inhibitor II
CAS#: 622855-50-9
Chemical Formula: C24H19ClN2O3
Exact Mass: 418.1084
Molecular Weight: 418.87
Elemental Analysis: C, 68.82; H, 4.57; Cl, 8.46; N, 6.69; O, 11.46
The following data is based on the product molecular weight 418.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
