Echinosporin | CAS#79127-35-8

MedKoo Cat#: 341450 | Name: Echinosporin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Echinosporin is a biochemical.

Chemical Structure

Echinosporin

CAS#79127-35-8

Theoretical Analysis

MedKoo Cat#: 341450

Name: Echinosporin

CAS#: 79127-35-8

Chemical Formula: C10H9NO5

Exact Mass: 223.0481

Molecular Weight: 223.18

Elemental Analysis: C, 53.82; H, 4.06; N, 6.28; O, 35.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Echinosporin; XK-213; XK 213; XK213.

IUPAC/Chemical Name

1,5-(Epoxymethano)cyclopenta(c)pyran-3-carboxamide, 1,4a,5,7a-tetrahydro-5-hydroxy-8-oxo-, (1S-(1-alpha,4a-beta,5-beta,7a-beta))-

InChi Key

OXSZHYWOGQJUST-OFCCZVAHSA-N

InChi Code

InChI=1S/C10H9NO5/c11-7(12)6-3-5-4-1-2-10(5,14)9(13)16-8(4)15-6/h1-5,8,14H,(H2,11,12)/t4-,5+,8-,10+/m1/s1

SMILES Code

O=C(C1=C[C@@]([C@@](C(O2)=O)(O)C=C3)([H])[C@]3([H])[C@]2([H])O1)N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 223.18 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Dame ZT, Islam MT, Helmke E, von Tiedemann A, Laatsch H. Oligomycins and pamamycin homologs impair motility and induce lysis of zoospores of the grapevine downy mildew pathogen, Plasmopara viticola. FEMS Microbiol Lett. 2016 Aug;363(16). pii: fnw167. doi: 10.1093/femsle/fnw167. Epub 2016 Jun 27. PubMed PMID: 27354061. 2: Lankapalli AR, Kannabiran K. Interaction of marine Streptomyces compounds with selected cancer drug target proteins by in silico molecular docking studies. Interdiscip Sci. 2013 Mar;5(1):37-44. doi: 10.1007/s12539-013-0146-0. Epub 2013 Apr 19. PubMed PMID: 23605638. 3: Flasz JT, Hale KJ. A new stereocontrolled synthetic route to (-)-echinosporin from D-glucose via Padwa allenylsulfone [3 + 2]-anionic cycloadditive elimination. Org Lett. 2012 Jun 15;14(12):3024-7. doi: 10.1021/ol301090v. Epub 2012 May 30. PubMed PMID: 22646909. 4: Cui CB, Liu HB, Gu JY, Gu QQ, Cai B, Zhang DY, Zhu TJ. Echinosporins as new cell cycle inhibitors and apoptosis inducers from marine-derived Streptomyces albogriseolus. Fitoterapia. 2007 Apr;78(3):238-40. Epub 2007 Feb 6. PubMed PMID: 17376609. 5: Morimoto M, Imai R. Antitumor activity of echinosporin. J Antibiot (Tokyo). 1985 Apr;38(4):490-5. PubMed PMID: 4008342. 6: Sato T, Kawamoto I, Oka T, Okachi R. A new antibiotic echinosporin (XK-213) - producing organism, isolation and characterization. J Antibiot (Tokyo). 1982 Mar;35(3):266-71. PubMed PMID: 7076574.