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MedKoo Cat#: 341430 | Name: Lidocaine
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Lidocaine is a biochemical.

Chemical Structure

Lidocaine
Lidocaine
CAS#137-58-6

Theoretical Analysis

MedKoo Cat#: 341430

Name: Lidocaine

CAS#: 137-58-6

Chemical Formula: C14H22N2O

Exact Mass: 234.1732

Molecular Weight: 234.34

Elemental Analysis: C, 71.76; H, 9.46; N, 11.95; O, 6.83

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
10g USD 350.00 2 Weeks
25g USD 650.00 2 Weeks
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Related CAS #
No Data
Synonym
Lidocaine; NSC-40030; NSC 40030; NSC40030;
IUPAC/Chemical Name
2',6'-Acetoxylidide, 2-(diethylamino)-
InChi Key
NNJVILVZKWQKPM-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
SMILES Code
O=C(NC1=C(C)C=CC=C1C)CN(CC)CC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 234.34 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kwon SY, Chung SW, Joo JD. Optimal neuromuscular blocking effects of remifentanil during tracheal intubation under general anesthesia. J Int Med Res. 2018 Jan 1:300060518772227. doi: 10.1177/0300060518772227. [Epub ahead of print] PubMed PMID: 29722285. 2: Shields LBE, Iyer VG, Zhang YP, Shields CB. Acute cauda equina syndrome following orthopedic procedures as a result of epidural anesthesia. Surg Neurol Int. 2018 Apr 10;9:81. doi: 10.4103/sni.sni_492_17. eCollection 2018. PubMed PMID: 29721359; PubMed Central PMCID: PMC5909088. 3: Levy A, Matharu MS. Short-Lasting Unilateral Neuralgiform Headache Attacks. Ann Indian Acad Neurol. 2018 Apr;21(Suppl 1):S31-S38. doi: 10.4103/aian.AIAN_356_17. Review. PubMed PMID: 29720816; PubMed Central PMCID: PMC5909132. 4: Petersilka GJ, Arweiler NB, Otto J, Wittig T. Non-interventional study to collect data for the application of lidocaine gel 2% during scaling and root planing and professional mechanical plaque removal. Clin Oral Investig. 2018 May 1. doi: 10.1007/s00784-018-2468-0. [Epub ahead of print] PubMed PMID: 29717361. 5: Gottlieb M. Current Approach to the Diagnosis and Management of Shoulder Dislocation in Children. Pediatr Emerg Care. 2018 May;34(5):357-362. doi: 10.1097/PEC.0000000000001474. PubMed PMID: 29715217. 6: Donaldson M, Goodchild JH. Lidocaine turns 70: the evolution of dental local anesthesia. Gen Dent. 2018 May-Jun;66(3):6-9. PubMed PMID: 29714692. 7: Gasparini G, Saponaro G, Gasparini D, Foresta E, Azzuni C, Adduci A, Boniello R, Moro A, De Angelis P, Di Nardo F, Damato G, Doneddu P, Todaro M, Garagiola U, Pelo S. The Use of Ropivacaine in Therapeutic Treatment of Oral Aphthosis. Biomed Res Int. 2018 Mar 11;2018:1868254. doi: 10.1155/2018/1868254. eCollection 2018. PubMed PMID: 29713640; PubMed Central PMCID: PMC5866890. 8: Dernek B, Adiyeke L, Duymus TM, Gokcedag A, Kesiktas FN, Aksoy C. Efficacy of Trigger Point Injections in Patients with Lumbar Disc Hernia without Indication for Surgery. Asian Spine J. 2018 Apr;12(2):232-237. doi: 10.4184/asj.2018.12.2.232. Epub 2018 Apr 16. PubMed PMID: 29713403; PubMed Central PMCID: PMC5913013. 9: Ghoddusi J, Zarrabi MH, Daneshvar F, Naghavi N. Efficacy of IANB and Gow-Gates Techniques in Mandibular Molars with Symptomatic Irreversible Pulpitis: A Prospective Randomized Double Blind Clinical Study. Iran Endod J. 2018 Spring;13(2):143-148. doi: 10.22037/iej.v13i2.18625. PubMed PMID: 29707005; PubMed Central PMCID: PMC5911284. 10: Elgebaly AS. Does the Use of Nitroglycerin Patch Improve Local Anaesthetic Effects in Bier's Block? A Double-Blind Placebo Controlled Study. Anesthesiol Res Pract. 2018 Mar 7;2018:9674731. doi: 10.1155/2018/9674731. eCollection 2018. PubMed PMID: 29706996; PubMed Central PMCID: PMC5863317. 11: Zhang Z, Chen Y, Wang E, Wu L, Wang R, Song Z, Weng Y, Sun Z, Guo Q, Li Y. Sufentanil Alleviates Intrathecal Lidocaine Induced Prolonged Sensory and Motor Impairments but not the Spinal Histological Injury in Rats. Neurochem Res. 2018 Apr 27. doi: 10.1007/s11064-018-2524-9. [Epub ahead of print] PubMed PMID: 29704143. 12: Sun X, Xu Y, Zhang X, Li A, Zhang H, Yang T, Liu Y. Topical pharyngeal anesthesia provides no additional benefit to propofol sedation for esophagogastroduodenoscopy: a randomized controlled double-blinded clinical trial. Sci Rep. 2018 Apr 27;8(1):6682. doi: 10.1038/s41598-018-25164-7. PubMed PMID: 29703990; PubMed Central PMCID: PMC5923272. 13: Council ML, Hruza GJ. Commentary on Bupivacaine as an Adjunct to Lidocaine in Mohs Micrographic Surgery. Dermatol Surg. 2018 May;44(5):611-612. doi: 10.1097/DSS.0000000000001399. PubMed PMID: 29701617. 14: Patel BK, Wendlandt BN, Wolfe KS, Patel SB, Doman E, Pohlman AS, Hall JB, Kress JP. Comparison of Two Lidocaine Administration Techniques on Perceived Pain from Bedside Procedures: A Randomized Clinical Trial. Chest. 2018 Apr 23. pii: S0012-3692(18)30630-5. doi: 10.1016/j.chest.2018.04.018. [Epub ahead of print] PubMed PMID: 29698720. 15: Liu H, Lu F, Zhou D, Yin Y, Li J, Yang B, Song L, Ye L, Xiao H. The Analgesic and Emotional Response to Intravenous Lidocaine Infusion in the Treatment of Postherpetic Neuralgia: A Randomized, Double-Blinded, Placebo-Controlled Study. Clin J Pain. 2018 Apr 25. doi: 10.1097/AJP.0000000000000623. [Epub ahead of print] PubMed PMID: 29698250. 16: Sahmeddini MA, Khosravi MB, Seyedi M, Hematfar Z, Abbasi S, Farbood A. Comparison of Magnesium Sulfate and Tramadol as an Adjuvant to Intravenous Regional Anesthesia for Upper Extremity Surgeries. Anesth Pain Med. 2017 Dec 27;7(6):e57102. doi: 10.5812/aapm.57102. eCollection 2017 Dec. PubMed PMID: 29696122; PubMed Central PMCID: PMC5903376. 17: Zaman B, Hojjati Ashrafi S, Seyed Siamdoust S, Hassani V, Mohamad Taheri S, Noorizad S. The Effect of Ketamine and Dexamethasone in Combination with Lidocaine on the Onset and Duration of Axillary Block in Hand and Forearm Soft Tissue Surgery. Anesth Pain Med. 2017 Oct 16;7(5):e15570. doi: 10.5812/aapm.15570. eCollection 2017 Oct. PubMed PMID: 29696115; PubMed Central PMCID: PMC5903223. 18: Justin R, Chen B. Multifunctional chitosan-magnetic graphene quantum dot nanocomposites for the release of therapeutics from detachable and non-detachable biodegradable microneedle arrays. Interface Focus. 2018 Jun 6;8(3):20170055. doi: 10.1098/rsfs.2017.0055. Epub 2018 Apr 20. PubMed PMID: 29696087; PubMed Central PMCID: PMC5915657. 19: Kaka U, Rahman NA, Abubakar AA, Goh YM, Fakurazi S, Omar MA, Chen HC. Pre-emptive multimodal analgesia with tramadol and ketamine-lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy. J Pain Res. 2018 Apr 11;11:743-752. doi: 10.2147/JPR.S152475. eCollection 2018. PubMed PMID: 29695926; PubMed Central PMCID: PMC5905489. 20: Kutlesic RM, Popovic J, Stefanovic M, Vukomanovic P, Lukic B, Lilic G. ALTERNATIVES OF MENOPAUSAL HORMONE THERAPY. Med Pregl. 2016 Oct;69(5-6):177-182. PubMed PMID: 29693846.