MedKoo Cat#: 341326 | Name: Rhodamine 123 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

The laser dye rhodamine 123 is also used in biochemistry to inhibit mitochondrion function.

Chemical Structure

Rhodamine 123 free base
Rhodamine 123 free base
CAS#104114-27-4

Theoretical Analysis

MedKoo Cat#: 341326

Name: Rhodamine 123 free base

CAS#: 104114-27-4

Chemical Formula: C21H16N2O3

Exact Mass: 344.1161

Molecular Weight: 344.37

Elemental Analysis: C, 73.24; H, 4.68; N, 8.13; O, 13.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Rhodamine 123 free base;
IUPAC/Chemical Name
Xanthylium, 3,6-diamino-9-(2-(methoxycarbonyl)phenyl)-
InChi Key
FCGVBHISQBBIQF-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H16N2O3/c1-25-21(24)15-5-3-2-4-14(15)20-16-8-6-12(22)10-18(16)26-19-11-13(23)7-9-17(19)20/h2-11,22H,23H2,1H3
SMILES Code
COC(c1c(c(c(ccc(N)c2)c2o3)c4c3cc(=N)cc4)cccc1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 344.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sperandio FF, Sharma SK, Wang M, Jeon S, Huang YY, Dai T, Nayka S, de Sousa SC, Chiang LY, Hamblin MR. Photoinduced electron-transfer mechanisms for radical-enhanced photodynamic therapy mediated by water-soluble decacationic C₇₀ and C₈₄O₂ Fullerene Derivatives. Nanomedicine. 2013 May;9(4):570-9. doi: 10.1016/j.nano.2012.09.005. Epub 2012 Oct 29. PubMed PMID: 23117043; PubMed Central PMCID: PMC3582824. 2: Graham A, Li G, Chen Y, Morgan J, Oseroff A, Dougherty TJ, Pandey RK. Structure-activity relationship of new octaethylporphyrin-based benzochlorins as photosensitizers for photodynamic therapy. Photochem Photobiol. 2003 May;77(5):561-6. PubMed PMID: 12812301. 3: Kelly SP, Fletcher M, Pärt P, Wood CM. Procedures for the preparation and culture of 'reconstructed' rainbow trout branchial epithelia. Methods Cell Sci. 2000;22(2-3):153-63. PubMed PMID: 11264949. 4: Hirsch-Ernst KI, Ziemann C, Schmitz-Salue C, Foth H, Kahl GF. Modulation of P-glycoprotein and mdr1b mRNA expression by growth factors in primary rat hepatocyte culture. Biochem Biophys Res Commun. 1995 Oct 4;215(1):179-85. PubMed PMID: 7575588. 5: Lee JS, Paull K, Alvarez M, Hose C, Monks A, Grever M, Fojo AT, Bates SE. Rhodamine efflux patterns predict P-glycoprotein substrates in the National Cancer Institute drug screen. Mol Pharmacol. 1994 Oct;46(4):627-38. PubMed PMID: 7969041. 6: Morliere P, Mangel WF, Santus R, Huppe G, Reyftmann JP, Kohen E. Interaction of tetrapyrrolic rings with rhodamine 110 and 123 and with rhodamine 110 derivatives bearing a peptidic side chain. Biochem Biophys Res Commun. 1987 Jul 15;146(1):107-13. PubMed PMID: 3038101.