MedKoo Cat#: 562574 | Name: 2OH-BNPP1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

2OH-BNPP1 is an inhibitor of the kinase activity of BUB1.

Chemical Structure

2OH-BNPP1
2OH-BNPP1
CAS#833481-73-5

Theoretical Analysis

MedKoo Cat#: 562574

Name: 2OH-BNPP1

CAS#: 833481-73-5

Chemical Formula: C16H19N5O

Exact Mass: 297.1590

Molecular Weight: 297.36

Elemental Analysis: C, 64.63; H, 6.44; N, 23.55; O, 5.38

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
10mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
2OH-BNPP1; 2OHBNPP1; 2OH BNPP1;
IUPAC/Chemical Name
2-[(4-Amino-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)methyl]phenol
InChi Key
LWLCFWPPMNPMOI-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H19N5O/c1-16(2,3)21-15-13(14(17)18-9-19-15)11(20-21)8-10-6-4-5-7-12(10)22/h4-7,9,22H,8H2,1-3H3,(H2,17,18,19)
SMILES Code
OC1=CC=CC=C1CC2=NN(C(C)(C)C)C3=NC=NC(N)=C32
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 297.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Nyati S, Schinske-Sebolt K, Pitchiaya S, Chekhovskiy K, Chator A, Chaudhry N, Dosch J, Van Dort ME, Varambally S, Kumar-Sinha C, Nyati MK, Ray D, Walter NG, Yu H, Ross BD, Rehemtulla A. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8(358):ra1. doi: 10.1126/scisignal.2005379. PubMed PMID: 25564677; PubMed Central PMCID: PMC4440544.