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MedKoo Cat#: 562541 | Name: DC_501

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DC_501 is a selective non-nucleoside inhibitor of DNA methyltransferase 1 (DNMT1).

Chemical Structure

DC_501
DC_501
CAS#889797-65-3

Theoretical Analysis

MedKoo Cat#: 562541

Name: DC_501

CAS#: 889797-65-3

Chemical Formula: C25H23Cl2N3O

Exact Mass: 451.1218

Molecular Weight: 452.37

Elemental Analysis: Chemical Formula: C25H23Cl2N3O Exact Mass: 451.1218 Molecular Weight: 452.3790 Elemental Analysis: C, 66.38; H, 5.12; Cl, 15.67; N, 9.29; O, 3.54

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
DC_501; DC 501; DC501;
IUPAC/Chemical Name
1-((2-(1H-Indol-3-yl)ethyl)amino)-3-(3,6-dichloro-9H-carbazol-9-yl)-propan-2-ol
InChi Key
BBTFHKNAZNYZNG-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H23Cl2N3O/c26-17-5-7-24-21(11-17)22-12-18(27)6-8-25(22)30(24)15-19(31)14-28-10-9-16-13-29-23-4-2-1-3-20(16)23/h1-8,11-13,19,28-29,31H,9-10,14-15H2
SMILES Code
OC(CN1C2=C(C3=C1C=CC(Cl)=C3)C=C(Cl)C=C2)CNCCC4=CNC5=C4C=CC=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 452.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Chen S, Wang Y, Zhou W, Li S, Peng J, Shi Z, Hu J, Liu YC, Ding H, Lin Y, Li L, Cheng S, Liu J, Lu T, Jiang H, Liu B, Zheng M, Luo C. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57(21):9028-41. doi: 10.1021/jm501134e. Epub 2014 Nov 4. PubMed PMID: 25333769.