MedKoo Cat#: 562537 | Name: AMG7905

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AMG7905 is a transient receptor potential vanilloid type 1 modulator.

Chemical Structure

AMG7905
AMG7905
CAS#1026876-55-0

Theoretical Analysis

MedKoo Cat#: 562537

Name: AMG7905

CAS#: 1026876-55-0

Chemical Formula: C25H24F3N5S

Exact Mass: 483.1705

Molecular Weight: 483.55

Elemental Analysis: C, 62.10; H, 5.00; F, 11.79; N, 14.48; S, 6.63

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
AMG7905; AMG-7905; AMG 7905;
IUPAC/Chemical Name
N-[6-[2-[(Cyclohexylmethyl)amino]-4-(trifluoromethyl)phenyl]-4-pyrimidinyl]-6-benzothiazolamine
InChi Key
HDEGHWQWPSXKSF-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H24F3N5S/c26-25(27,28)17-6-8-19(21(10-17)29-13-16-4-2-1-3-5-16)22-12-24(31-14-30-22)33-18-7-9-20-23(11-18)34-15-32-20/h6-12,14-16,29H,1-5,13H2,(H,30,31,33)
SMILES Code
FC(C1=CC=C(C2=CC(NC3=CC=C4N=CSC4=C3)=NC=N2)C(NCC5CCCCC5)=C1)(F)F
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 483.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Garami A, Pakai E, McDonald HA, Reilly RM, Gomtsyan A, Corrigan JJ, Pinter E, Zhu DXD, Lehto SG, Gavva NR, Kym PR, Romanovsky AA. TRPV1 antagonists that cause hypothermia, instead of hyperthermia, in rodents: Compounds' pharmacological profiles, in vivo targets, thermoeffectors recruited and implications for drug development. Acta Physiol (Oxf). 2018 Jan 20. doi: 10.1111/apha.13038. [Epub ahead of print] PubMed PMID: 29352512.