MedKoo Cat#: 562531 | Name: YLT192

Description:

WARNING: This product is for research use only, not for human or veterinary use.

YLT192 is an orally active and bioavailable inhibitor of VEGFR2 signaling with potent antiangiogenic activity and antitumor efficacy.

Chemical Structure

YLT192
YLT192
CAS#1246566-47-1

Theoretical Analysis

MedKoo Cat#: 562531

Name: YLT192

CAS#: 1246566-47-1

Chemical Formula: C21H19N3O4

Exact Mass: 377.1376

Molecular Weight: 377.40

Elemental Analysis: C, 66.83; H, 5.07; N, 11.13; O, 16.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
YLT192; YLT-192; YLT 192;
IUPAC/Chemical Name
4-[4-[(3-Methoxybenzoyl)amino]phenoxy]-N-methyl-2-pyridinecarboxamide
InChi Key
VEAFCVREGPWSCO-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H19N3O4/c1-22-21(26)19-13-18(10-11-23-19)28-16-8-6-15(7-9-16)24-20(25)14-4-3-5-17(12-14)27-2/h3-13H,1-2H3,(H,22,26)(H,24,25)
SMILES Code
O=C(C1=NC=CC(OC2=CC=C(NC(C3=CC=CC(OC)=C3)=O)C=C2)=C1)NC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 377.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Todescan S, Nizar R. Managing patients with necrotizing ulcerative periodontitis. J Can Dent Assoc. 2013;79:d44. Review. PubMed PMID: 23763731. 2: Titball RW. Clostridium perfringens vaccines. Vaccine. 2009 Nov 5;27 Suppl 4:D44-7. doi: 10.1016/j.vaccine.2009.07.047. Review. PubMed PMID: 19837285. 3: Bieniasz PD, Cullen BR. Chemokine receptors and human immunodeficiency virus infection. Front Biosci. 1998 Jan 1;3:d44-58. Review. PubMed PMID: 9407151. 4: Autran B, Plata F, Guillon JM, Joly P, Mayaud C, Debré P. HIV-specific cytotoxic T lymphocytes directed against alveolar macrophages in HIV-infected patients. Res Virol. 1990 Mar-Apr;141(2):131-6. Review. PubMed PMID: 2189171.