D44 | CAS#826998-10-1 | Plasmodium FKBP inhibitor

MedKoo Cat#: 562530 | Name: D44

Description:

WARNING: This product is for research use only, not for human or veterinary use.

D44 is an inhibitor of Plasmodium FKBPs.

Chemical Structure

D44

CAS#826998-10-1

Theoretical Analysis

MedKoo Cat#: 562530

Name: D44

CAS#: 826998-10-1

Chemical Formula: C16H16N4OS

Exact Mass: 312.1045

Molecular Weight: 312.39

Elemental Analysis: C, 61.52; H, 5.16; N, 17.94; O, 5.12; S, 10.26

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

D44; D-44; D 44;

IUPAC/Chemical Name

N-(2-Ethyl-phenyl)-2-(3H-imidazo[4,5-b]pyridin-2-ylsulfanyl)-acetamide

InChi Key

LGTSSAOGGPBTGN-UHFFFAOYSA-N

InChi Code

InChI=1S/C16H16N4OS/c1-2-11-6-3-4-7-12(11)18-14(21)10-22-16-19-13-8-5-9-17-15(13)20-16/h3-9H,2,10H2,1H3,(H,18,21)(H,17,19,20)

SMILES Code

O=C(NC1=CC=CC=C1CC)CSC2=NC3=CC=CN=C3N2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 312.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Todescan S, Nizar R. Managing patients with necrotizing ulcerative periodontitis. J Can Dent Assoc. 2013;79:d44. Review. PubMed PMID: 23763731. 2: Titball RW. Clostridium perfringens vaccines. Vaccine. 2009 Nov 5;27 Suppl 4:D44-7. doi: 10.1016/j.vaccine.2009.07.047. Review. PubMed PMID: 19837285. 3: Bieniasz PD, Cullen BR. Chemokine receptors and human immunodeficiency virus infection. Front Biosci. 1998 Jan 1;3:d44-58. Review. PubMed PMID: 9407151. 4: Autran B, Plata F, Guillon JM, Joly P, Mayaud C, Debré P. HIV-specific cytotoxic T lymphocytes directed against alveolar macrophages in HIV-infected patients. Res Virol. 1990 Mar-Apr;141(2):131-6. Review. PubMed PMID: 2189171.