MedKoo Cat#: 527863 | Name: TC-AQP1-1
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TC-AQP1-1 is an aquaporin 1 (AQP1) channel blocker.

Chemical Structure

TC-AQP1-1
TC-AQP1-1
CAS#37710-81-9

Theoretical Analysis

MedKoo Cat#: 527863

Name: TC-AQP1-1

CAS#: 37710-81-9

Chemical Formula: C12H10O4

Exact Mass: 218.0579

Molecular Weight: 218.21

Elemental Analysis: C, 66.05; H, 4.62; O, 29.33

Price and Availability

Size Price Availability Quantity
100mg USD 650.00 2 Weeks
200mg USD 1,150.00 2 Weeks
500mg USD 2,450.00 2 Weeks
1g USD 3,250.00 2 Weeks
2g USD 5,950.00 2 Weeks
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Related CAS #
No Data
Synonym
TC-AQP1-1
IUPAC/Chemical Name
3,3'-(1,3-Phenylene)bis(2-propenoic acid)
InChi Key
KRXUBZPHAPGHPE-YDFGWWAZSA-N
InChi Code
InChI=1S/C12H10O4/c13-11(14)6-4-9-2-1-3-10(8-9)5-7-12(15)16/h1-8H,(H,13,14)(H,15,16)/b6-4+,7-5+
SMILES Code
O=C(O)/C=C/C1=CC=CC(/C=C/C(O)=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 218.21 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Snuggs, J. W., Bunning, R., & Le Maitre, C. L. (2021). Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4. eCells and Materials Journal, 41, 121-141. Salman, M. M., Kitchen, P., Yool, A. J., & Bill, R. M. (2022). Recent breakthroughs and future directions in drugging aquaporins. Trends in pharmacological sciences, 43(1), 30-42.