Synonym
X 14547-A; X 14547A; X 14547;
IUPAC/Chemical Name
2H-Pyran-2-acetic acid, 6-(1-ethyl-4-(1-ethyl-2,3,3a,4,5,7a-hexahydro-4-(1H-pyrrol-2-ylcarbonyl)-1H-inden-5-yl)-1,3-butadienyl)tetrahydro-alpha,5-dimethyl-, (1S-(1-alpha,3-alpha,beta,4-beta,5-beta(1E(2S*(S*),5R*,6S*),3E),7a-alpha))-
InChi Key
BAIPOTOKPGDCHA-MWBHXQFBSA-N
InChi Code
InChI=1S/C31H43NO4/c1-5-21-13-16-25-24(21)15-14-23(28(25)29(33)26-11-8-18-32-26)10-7-9-22(6-2)30-19(3)12-17-27(36-30)20(4)31(34)35/h7-11,14-15,18-21,23-25,27-28,30,32H,5-6,12-13,16-17H2,1-4H3,(H,34,35)/b10-7+,22-9+/t19-,20+,21-,23+,24+,25+,27+,28+,30+/m0/s1
SMILES Code
OC([C@@H]([C@@]1(O[C@H]([C@H](CC1)C)/C(CC)=C/C=C/[C@@H]2C=C[C@]3([H])[C@H](CC[C@]3([C@@H]2C(C4=CC=CN4)=O)[H])CC)[H])C)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
493.69
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
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2: Kuznetsova OS, Alenicheva NB, Ovchinnikova AG, Levit ZhD, Kuz'mina ED. [Various principles of detecting the producers of beta-lactamase inhibitors among soil Actinomycetes]. Antibiot Khimioter. 1988 Dec;33(12):895-900. Russian. PubMed PMID: 3072929.
3: Nagaraja TG, Taylor MB. Susceptibility and resistance of ruminal bacteria to antimicrobial feed additives. Appl Environ Microbiol. 1987 Jul;53(7):1620-5. PubMed PMID: 3116929; PubMed Central PMCID: PMC203920.
4: Caffarel-Mendez S, Jouany JP, Demuynck C. [In vitro study of ionophore antibiotics and various derivatives. I. Action on fermentation products in the rumen]. Reprod Nutr Dev. 1986;26(6):1295-303. French. PubMed PMID: 3823605.
5: Guyot J, Jeminet G, Debise R. Ionophoric activity of the antibiotic X.14547 A in the mitochondrial membrane. Experientia. 1984 Jun 15;40(6):551-3. PubMed PMID: 6427002.
6: Bartley EE, Nagaraja TG, Pressman ES, Dayton AD, Katz MP, Fina LR. Effects of lasalocid or monensin on legume or grain (feedlot) bloat. J Anim Sci. 1983 Jun;56(6):1400-6. PubMed PMID: 6874619.
7: Scherman D, Roisin MP, Henry JP, Jeminet G. Ionophore mediated catecholamine release from chromaffin granules. Comparison of X-537 A and X-14547 A effects. Biochem Pharmacol. 1981 Dec 15;30(24):3277-83. PubMed PMID: 7326036.
