MedKoo Cat#: 555221 | Name: MSX-130
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MSX-130 is CXCR4 Antagonist.

Chemical Structure

MSX-130
MSX-130
CAS#4051-59-6

Theoretical Analysis

MedKoo Cat#: 555221

Name: MSX-130

CAS#: 4051-59-6

Chemical Formula: C36H26N4

Exact Mass: 514.2157

Molecular Weight: 514.63

Elemental Analysis: C, 84.02; H, 5.09; N, 10.89

Price and Availability

Size Price Availability Quantity
10mg USD 150.00 Ready to ship
25mg USD 250.00 Ready to ship
50mg USD 425.00 Ready to ship
100mg USD 750.00 Ready to ship
200mg USD 1,250.00 Ready to ship
500mg USD 1,950.00 Ready to ship
1g USD 2,950.00 Ready to ship
2g USD 4,250.00 Ready to ship
5g USD 6,950.00 2 weeks
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Related CAS #
No Data
Synonym
MSX-130; MSX 130; MSX130.
IUPAC/Chemical Name
2,2'-(1,4-Phenylene)bis[4,5-diphenyl-1H-imidazole]
InChi Key
MKRQQXYFSWSAIS-UHFFFAOYSA-N
InChi Code
InChI=1S/C36H26N4/c1-5-13-25(14-6-1)31-32(26-15-7-2-8-16-26)38-35(37-31)29-21-23-30(24-22-29)36-39-33(27-17-9-3-10-18-27)34(40-36)28-19-11-4-12-20-28/h1-24H,(H,37,38)(H,39,40)
SMILES Code
C1(C2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2)=CC=C(C5=NC(C6=CC=CC=C6)=C(C7=CC=CC=C7)N5)C=C1
Appearance
Off-white to Pale Yellow Solid Powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Biological target:
MSX-130 is CXCR4 Antagonist.
In vitro activity:
TBD
In vivo activity:
TBD
Solvent mg/mL mM
Solubility
DMSO 3.0 5.83
Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 514.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
Zhan W, Liang Z, Zhu A, Kurtkaya S, Shim H, Snyder JP, Liotta DC. Discovery of small molecule CXCR4 antagonists. J Med Chem. 2007 Nov 15;50(23):5655-64. doi: 10.1021/jm070679i. Epub 2007 Oct 24. PMID: 17958344.