MedKoo Cat#: 527829 | Name: Bupicomide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bupicomide is a vasodilator, significantly reducing systolic, diastolic, and mean arterial pressure and peripheral vascular resistance.

Chemical Structure

Bupicomide
Bupicomide
CAS#22632-06-0

Theoretical Analysis

MedKoo Cat#: 527829

Name: Bupicomide

CAS#: 22632-06-0

Chemical Formula: C10H14N2O

Exact Mass: 178.1106

Molecular Weight: 178.24

Elemental Analysis: C, 67.39; H, 7.92; N, 15.72; O, 8.98

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Bupicomide
IUPAC/Chemical Name
5-Butylpyridine-2-carboxamide
InChi Key
VKSPIPWLHGKJQO-UHFFFAOYSA-N
InChi Code
InChI=1S/C10H14N2O/c1-2-3-4-8-5-6-9(10(11)13)12-7-8/h5-7H,2-4H2,1H3,(H2,11,13)
SMILES Code
O=C(C1=NC=C(CCCC)C=C1)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 178.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Velasco M, McNay JL. Physiologic mechanisms of bupicomide- and hydralazine-induced increase in plasma renin activity in hypertensive patients. Mayo Clin Proc. 1977 Jul;52(7):430-2. PubMed PMID: 875465. 2: Chrysant SG, Adamopoulos P, Tsuchiya M, Frohlich ED. Systemic and renal hemodynamic effects of bupicomide: a new vasodilator. Am Heart J. 1976 Sep;92(3):335-9. PubMed PMID: 782220. 3: Fung KK, Koda RT, Maronde RF, Cohen JL. Rapid GLC determination of fusaric acid in biological fluids. J Pharm Sci. 1976 Apr;65(4):596-08. PubMed PMID: 5590. 4: Velasco M, Gilbert CA, Rutledge CO, McNay JL. Antihypertensive effect of a dopamine beta hydroxylase inhibitor, bupicomide: a comparison with hydralazine. Clin Pharmacol Ther. 1975 Aug;18(2):145-53. PubMed PMID: 1097150.