MedKoo Cat#: 562439 | Name: ASP7663
Featured

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASP7663 is an orally bioavailable selective TRPA1 activator. It acts by stimulating 5-HT release from QGP-1 cells and exhibiting an abdominal analgesic effect in vivo.

Chemical Structure

ASP7663
ASP7663
CAS#1190217-35-6

Theoretical Analysis

MedKoo Cat#: 562439

Name: ASP7663

CAS#: 1190217-35-6

Chemical Formula: C14H14FNO3

Exact Mass: 263.0958

Molecular Weight: 263.26

Elemental Analysis: C, 63.87; H, 5.36; F, 7.22; N, 5.32; O, 18.23

Price and Availability

Size Price Availability Quantity
5mg USD 350.00 2 Weeks
10mg USD 550.00 2 Weeks
25mg USD 950.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
ASP7663; ASP-7663; ASP 7663;
IUPAC/Chemical Name
(2E)-2-[7-Fluoro-1,2-dihydro-1-(2-methylpropyl)-2-oxo-3H-indol-3-ylidene]acetic acid
InChi Key
RCVZUIGCNAAMIC-UXBLZVDNSA-N
InChi Code
InChI=1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
SMILES Code
O=C(O)/C=C1C(N(CC(C)C)C2=C/1C=CC=C2F)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 263.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kojima R, Nozawa K, Doihara H, Keto Y, Kaku H, Yokoyama T, Itou H. Effects of novel TRPA1 receptor agonist ASP7663 in models of drug-induced constipation and visceral pain. Eur J Pharmacol. 2014 Jan 15;723:288-93. doi: 10.1016/j.ejphar.2013.11.020. Epub 2013 Nov 28. PubMed PMID: 24291101.