MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 341223 | Name: Mefeserpine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mefeserpine is a biochemical.

Chemical Structure

Mefeserpine
Mefeserpine
CAS#3735-85-1

Theoretical Analysis

MedKoo Cat#: 341223

Name: Mefeserpine

CAS#: 3735-85-1

Chemical Formula: C32H38N2O8

Exact Mass: 578.2628

Molecular Weight: 578.66

Elemental Analysis: C, 66.42; H, 6.62; N, 4.84; O, 22.12

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Mefeserpine; Mefeserpinum; Mefeserpina.
IUPAC/Chemical Name
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[2-(4-methoxyphenoxy)acetyl]oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
InChi Key
KFDDPVMIQMFHBI-JLIPXIIDSA-N
InChi Code
InChI=1S/C32H38N2O8/c1-37-19-5-7-20(8-6-19)41-17-28(35)42-27-13-18-16-34-12-11-23-22-10-9-21(38-2)14-25(22)33-30(23)26(34)15-24(18)29(31(27)39-3)32(36)40-4/h5-10,14,18,24,26-27,29,31,33H,11-13,15-17H2,1-4H3/t18-,24+,26-,27-,29+,31+/m1/s1
SMILES Code
CO[C@H]1[C@H](OC(COC2=CC=C(OC)C=C2)=O)C[C@@H]3CN4CCC5=C(NC6=C5C=CC(OC)=C6)[C@H]4C[C@@H]3[C@@H]1C(OC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 578.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wang H, Fei Z, Li Z, Xing R, Liu Z, Zhang Y, Ding H. Coupling laser desorption with corona beam ionization for ambient mass spectrometric analysis of solution and powder samples. Talanta. 2018 Mar 1;179:364-368. doi: 10.1016/j.talanta.2017.11.039. Epub 2017 Nov 21. PubMed PMID: 29310245. 2: Kumar S, Singh A, Kumar B, Singh B, Bahadur L, Lal M. Simultaneous quantitative determination of bioactive terpene indole alkaloids in ethanolic extracts of Catharanthus roseus (L.) G. Don by ultra high performance liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2018 Mar 20;151:32-41. doi: 10.1016/j.jpba.2017.12.040. Epub 2017 Dec 25. PubMed PMID: 29304410. 3: Khafaie MA, Salvi SS, Ojha A, Khafaie B, Gore SD, Yajnik CS. Particulate matter and markers of glycemic control and insulin resistance in type 2 diabetic patients: result from Wellcome Trust Genetic study. J Expo Sci Environ Epidemiol. 2017 Dec 21. doi: 10.1038/s41370-017-0001-1. [Epub ahead of print] PubMed PMID: 29269753. 4: Jaiswal I, Jain A, Verma SK, Singh P, Kant S, Singh M. Effect of efflux pump inhibitors on the susceptibility of Mycobacterium tuberculosis to isoniazid. Lung India. 2017 Nov-Dec;34(6):499-505. doi: 10.4103/0970-2113.217567. PubMed PMID: 29098993; PubMed Central PMCID: PMC5684805. 5: Abramochkin DV, Pustovit KB, Kuz'min VS. Diadenosine Polyphosphates Suppress the Effects of Sympathetic Nerve Stimulation in Rabbit Heart Pacemaker. Bull Exp Biol Med. 2017 Sep;163(5):586-589. doi: 10.1007/s10517-017-3854-3. Epub 2017 Sep 25. PubMed PMID: 28948554. 6: Shendge AK, Basu T, Chaudhuri D, Panja S, Mandal N. In vitro Antioxidant and Antiproliferative Activities of Various Solvent Fractions from Clerodendrum viscosum Leaves. Pharmacogn Mag. 2017 Jul;13(Suppl 2):S344-S353. doi: 10.4103/pm.pm_395_16. Epub 2017 Jul 11. PubMed PMID: 28808404; PubMed Central PMCID: PMC5538178. 7: Mombeshora M, Mukanganyama S. Development of an accumulation assay and evaluation of the effects of efflux pump inhibitors on the retention of chlorhexidine digluconate in Pseudomonas aeruginosa and Staphylococcus aureus. BMC Res Notes. 2017 Jul 26;10(1):328. doi: 10.1186/s13104-017-2637-2. PubMed PMID: 28747232; PubMed Central PMCID: PMC5530522. 8: Osei Sekyere J, Amoako DG. Genomic and phenotypic characterisation of fluoroquinolone resistance mechanisms in Enterobacteriaceae in Durban, South Africa. PLoS One. 2017 Jun 21;12(6):e0178888. doi: 10.1371/journal.pone.0178888. eCollection 2017. PubMed PMID: 28636609; PubMed Central PMCID: PMC5479536. 9: Jo JH, Kim JH, Lee HS, Jeong GS, Lee JM, Lee S. Investigation of pharmacokinetic parameters of bakuchicin isolated from Psoralea corylifolia in mice. Fitoterapia. 2017 Jul;120:194-198. doi: 10.1016/j.fitote.2017.06.007. Epub 2017 Jun 8. PubMed PMID: 28602940. 10: Zhang Y, Zhang J, Cui P, Zhang Y, Zhang W. Identification of Novel Efflux Proteins Rv0191, Rv3756c, Rv3008, and Rv1667c Involved in Pyrazinamide Resistance in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2017 Jul 25;61(8). pii: e00940-17. doi: 10.1128/AAC.00940-17. Print 2017 Aug. PubMed PMID: 28584158; PubMed Central PMCID: PMC5527661. 11: Wang EH, Appulage DK, McAllister EA, Schug KA. Investigation of Ion Transmission Effects on Intact Protein Quantification in a Triple Quadrupole Mass Spectrometer. J Am Soc Mass Spectrom. 2017 Sep;28(9):1977-1986. doi: 10.1007/s13361-017-1696-x. Epub 2017 May 30. PubMed PMID: 28560561. 12: Li SL, Sun HM, Zhu BL, Liu F, Zhao HQ. Whole Genome Analysis Reveals New Insights into Macrolide Resistance in Mycoplasma pneumoniae. Biomed Environ Sci. 2017 May;30(5):343-350. doi: 10.3967/bes2017.045. PubMed PMID: 28549490. 13: Jennings MC, Forman ME, Duggan SM, Minbiole KPC, Wuest WM. Efflux Pumps Might Not Be the Major Drivers of QAC Resistance in Methicillin-Resistant Staphylococcus aureus. Chembiochem. 2017 Aug 17;18(16):1573-1577. doi: 10.1002/cbic.201700233. Epub 2017 Jun 27. PubMed PMID: 28510317; PubMed Central PMCID: PMC5664203. 14: Longo F, Mercatelli D, Novello S, Arcuri L, Brugnoli A, Vincenzi F, Russo I, Berti G, Mabrouk OS, Kennedy RT, Shimshek DR, Varani K, Bubacco L, Greggio E, Morari M. Age-dependent dopamine transporter dysfunction and Serine129 phospho-α-synuclein overload in G2019S LRRK2 mice. Acta Neuropathol Commun. 2017 Mar 14;5(1):22. doi: 10.1186/s40478-017-0426-8. PubMed PMID: 28292328; PubMed Central PMCID: PMC5351259. 15: Morris WE, Goldstein J, Redondo LM, Cangelosi A, Geoghegan P, Brocco M, Loidl FC, Fernandez-Miyakawa ME. Clostridium perfringens epsilon toxin induces permanent neuronal degeneration and behavioral changes. Toxicon. 2017 May;130:19-28. doi: 10.1016/j.toxicon.2017.02.019. Epub 2017 Feb 22. PubMed PMID: 28237716. 16: Moreira B, Tuoriniemi J, Kouchak Pour N, Mihalčíková L, Safina G. Surface Plasmon Resonance for Measuring Exocytosis from Populations of PC12 Cells: Mechanisms of Signal Formation and Assessment of Analytical Capabilities. Anal Chem. 2017 Mar 7;89(5):3069-3077. doi: 10.1021/acs.analchem.6b04811. Epub 2017 Feb 22. PubMed PMID: 28192972. 17: Wells JA, Shibata S, Fujikawa A, Takahashi M, Saga T, Aoki I. Functional MRI of the Reserpine-Induced Putative Rat Model of Fibromyalgia Reveals Discriminatory Patterns of Functional Augmentation to Acute Nociceptive Stimuli. Sci Rep. 2017 Jan 12;7:38325. doi: 10.1038/srep38325. PubMed PMID: 28079057; PubMed Central PMCID: PMC5228122. 18: Basu T, Panja S, Ghate NB, Chaudhuri D, Mandal N. Antioxidant and antiproliferative effects of different solvent fractions from Terminalia belerica Roxb. fruit on various cancer cells. Cytotechnology. 2017 Apr;69(2):201-216. doi: 10.1007/s10616-016-0051-6. Epub 2016 Dec 21. PubMed PMID: 28004224; PubMed Central PMCID: PMC5366960. 19: Berg T. M-currents (Kv7.2-7.3/KCNQ2-KCNQ3) Are Responsible for Dysfunctional Autonomic Control in Hypertensive Rats. Front Physiol. 2016 Nov 29;7:584. eCollection 2016. PubMed PMID: 27965589; PubMed Central PMCID: PMC5126116. 20: Maze M. From Bench to Bedside and Back Again: A Personal Journey with Dexmedetomidine. Anesthesiology. 2016 Sep;125(3):590-4. doi: 10.1097/ALN.0000000000001214. Review. PubMed PMID: 27348818; PubMed Central PMCID: PMC5394927.