Synonym
LASSBio-1359; LASSBio 1359; LASSBio1359;
IUPAC/Chemical Name
Benzoic acid, (2E)-2-[(3,4-dimethoxyphenyl)methylene]-1-methylhydrazide
InChi Key
ZKKIMIBBUMDNHP-LDADJPATSA-N
InChi Code
InChI=1S/C17H18N2O3/c1-19(17(20)14-7-5-4-6-8-14)18-12-13-9-10-15(21-2)16(11-13)22-3/h4-12H,1-3H3/b18-12+
SMILES Code
O=C(N(C)/N=C/C1=CC=C(OC)C(OC)=C1)C2=CC=CC=C2
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
298.34
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Montes GC, Hammes N, da Rocha MD, Montagnoli TL, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Treatment with Adenosine Receptor Agonist Ameliorates Pain Induced by Acute and Chronic Inflammation. J Pharmacol Exp Ther. 2016 Aug;358(2):315-23. doi: 10.1124/jpet.115.231241. Epub 2016 May 18. PubMed PMID: 27194479.
2: Moura VJ, Alencar AK, Calasans-Maia Jde A, da Silva JS, Fraga CA, Zapata-Sudo G, Barreiro EJ, Sudo RT. Novel agonist of adenosine receptor induces relaxation of corpus cavernosum in guinea pigs: an in vitro and in vivo study. Urology. 2015 May;85(5):1214.e17-21. doi: 10.1016/j.urology.2015.02.006. PubMed PMID: 25917739.
3: Alencar AK, Pereira SL, Montagnoli TL, Maia RC, Kümmerle AE, Landgraf SS, Caruso-Neves C, Ferraz EB, Tesch R, Nascimento JH, de Sant'Anna CM, Fraga CA, Barreiro EJ, Sudo RT, Zapata-Sudo G. Beneficial effects of a novel agonist of the adenosine A2A receptor on monocrotaline-induced pulmonary hypertension in rats. Br J Pharmacol. 2013 Jul;169(5):953-62. doi: 10.1111/bph.12193. PubMed PMID: 23530610; PubMed Central PMCID: PMC3696320.
