MedKoo Cat#: 562385 | Name: UNC2327
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3).

Chemical Structure

UNC2327
UNC2327
CAS#1426152-53-5

Theoretical Analysis

MedKoo Cat#: 562385

Name: UNC2327

CAS#: 1426152-53-5

Chemical Formula: C14H17N5O2S

Exact Mass: 319.1103

Molecular Weight: 319.38

Elemental Analysis: C, 52.65; H, 5.37; N, 21.93; O, 10.02; S, 10.04

Price and Availability

Size Price Availability Quantity
5mg USD 400.00
10mg USD 600.00
25mg USD 900.00
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Related CAS #
No Data
Synonym
UNC2327; UNC-2327; UNC 2327;
IUPAC/Chemical Name
N-1,2,3-Benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]urea
InChi Key
MYTRGTBDVGKKRO-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
SMILES Code
O=C(NCC(N1CCCCC1)=O)NC2=CC=C3N=NSC3=C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 319.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Sun Y, Zhao B, Wang Y, Chen Z, Zhang H, Qu L, Zhao Y, Song J. Optimization of potential non-covalent inhibitors for the SARS-CoV-2 main protease inspected by a descriptor of the subpocket occupancy. Phys Chem Chem Phys. 2022 Dec 14;24(48):29940-29951. doi: 10.1039/d2cp03681a. PMID: 36468652.