Sortin2 | CAS#372972-39-9 | sorting inhibitor

MedKoo Cat#: 562363 | Name: Sortin2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sortin2 is a sorting inhibitor. It increases lateral root occurrence by acting upstream from the morphological marker of lateral root primordium formation, the mitotic activity.

Chemical Structure

Sortin2

CAS#372972-39-9

Theoretical Analysis

MedKoo Cat#: 562363

Name: Sortin2

CAS#: 372972-39-9

Chemical Formula: C16H12ClNO5S3

Exact Mass: 428.9566

Molecular Weight: 429.90

Elemental Analysis: C, 44.70; H, 2.81; Cl, 8.25; N, 3.26; O, 18.61; S, 22.37

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Sortin2; Sortin-2; Sortin 2;

IUPAC/Chemical Name

5-[[5-(3-Chlorophenyl)-2-furanyl]methylene]-4-oxo-2-thioxo-3-thiazolidineethanesulfonic acid

InChi Key

CUKZYGAOTUDVNI-NTEUORMPSA-N

InChi Code

InChI=1S/C16H12ClNO5S3/c17-11-3-1-2-10(8-11)13-5-4-12(23-13)9-14-15(19)18(16(24)25-14)6-7-26(20,21)22/h1-5,8-9H,6-7H2,(H,20,21,22)/b14-9+

SMILES Code

O=S(CCN(C/1=O)C(SC1=C\C2=CC=C(C3=CC=CC(Cl)=C3)O2)=S)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 429.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Vásquez-Soto B, Manríquez N, Cruz-Amaya M, Zouhar J, Raikhel NV, Norambuena L. Sortin2 enhances endocytic trafficking towards the vacuole in Saccharomyces cerevisiae. Biol Res. 2015 Jul 25;48:39. doi: 10.1186/s40659-015-0032-9. PubMed PMID: 26209329; PubMed Central PMCID: PMC4515019. 2: Pérez-Henríquez P, Raikhel NV, Norambuena L. Endocytic trafficking towards the vacuole plays a key role in the auxin receptor SCF(TIR)-independent mechanism of lateral root formation in A. thaliana. Mol Plant. 2012 Nov;5(6):1195-209. doi: 10.1093/mp/sss066. Epub 2012 Jul 30. PubMed PMID: 22848095. 3: Norambuena L, Zouhar J, Hicks GR, Raikhel NV. Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae. BMC Chem Biol. 2008 Jan 7;8:1. doi: 10.1186/1472-6769-8-1. PubMed PMID: 18179719; PubMed Central PMCID: PMC2265672.