MedKoo Cat#: 581154 | Name: Bis(diazoacetyl)butane

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Bis(diazoacetyl)butane is also known as DAB (1,4-bisdiazoacetyl butane), it is a mutagen and traditionally related to radio-mimetic chemical mutagens due to the similarity of appearance of mutagenic action of this mutagen and physical mutagens such as gamma and x-rays. Bis(diazoacetyl)butane has anti-tumor and carcinogenic activity.

Chemical Structure

Bis(diazoacetyl)butane
Bis(diazoacetyl)butane
CAS#1448-16-4

Theoretical Analysis

MedKoo Cat#: 581154

Name: Bis(diazoacetyl)butane

CAS#: 1448-16-4

Chemical Formula: C6H8N4O

Exact Mass: 152.0698

Molecular Weight: 152.16

Elemental Analysis: C, 47.36; H, 5.30; N, 36.82; O, 10.51

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Bis(diazoacetyl)butane; DAB (mutagen); Supermutagen; 1,4-Bis(diazoacetyl)butane; 1,4-Bis-diazoacetylbutane;
IUPAC/Chemical Name
1,4-Bis-diazoacetylbutane
InChi Key
IPWXWJXIGXOPQP-UHFFFAOYSA-N
InChi Code
InChI=1S/C6H8N4O/c1-5(11)6(10-8)3-2-4-9-7/h4H,2-3H2,1H3
SMILES Code
[N-]=[N+]=CCCC(C(C)=O)=[N+]=[N-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 152.16 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Aslanian MM, Kim AI, Smirnova VA. [Characteristics of the mutagenic action of 1,4-bis-diazoacetylbutane on mature Drosophila melanogaster sperm]. Genetika. 1981;17(4):677-83. Russian. PubMed PMID: 6785154. 2: Shigaeva MKh, Akhmatullina NB, Dzhangalina NK. [Effect of nonmutagenic doses of 1,4-bis-diazoacetylbutane on Streptomyces griseus]. Mikrobiologiia. 1982 Nov-Dec;51(6):993-6. Russian. PubMed PMID: 6818438. 3: Ivanovskiĭ IuA, Kulinich NM. [Stimulating action of gamma irradiation and alkylating compounds on the brine shrimp, Artemia salina. 3. 3H-thymidine and 3H-uridine incorporation into the nauplii of A. salina irradiated or treated with 1-4-bis-diazoacetylbutane at the embryonic diapause stage]. Radiobiologiia. 1980 May-Jun;20(3):414-8. Russian. PubMed PMID: 7406993. 4: Gorbunova NA, Sukharevich ME, Iakovleva EP. [Natural and induced variability of pathogen, producing antifungal antibiotic, imbrimycin]. Antibiot Khimioter. 1998;43(3):3-7. Russian. PubMed PMID: 9606489. 5: Ivanovskiĭ IuA. [Stimulating effect of gamma-irradiation and alkylating compounds on the branchiopod crustacean Artemia salina. 2. Effect of gamma-radiation and chemical mutagens on the growth of A. salina]. Radiobiologiia. 1980 Mar-Apr;20(2):303-6. Russian. PubMed PMID: 7406992.